| outbreaks of pneumocystis carinii pneumonia in colonies of immunodeficient mice. | outbreaks of pneumocystis carinii pneumonia occurred in colonies of nu/nu and scid/scid mice at four different institutions. the disease, which was characterized by chronic wasting and respiratory insufficiency, was more severe in older mice and in animals housed in cages with special protective tops. histopathologic features included alveolar filling with the typical foamy honeycomb material and a mild, nonspecific host inflammatory response. immunofluorescence and immunoblotting studies sugges ... | 1989 | 2642471 |