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demonstration that a case of human alveolar echinococcosis in minnesota in 1977 was caused by the n2 strain.alveolar echinococcosis is the most serious helminthic zoonosis of the northern hemisphere affecting humans. the causative agent, echinococcus multilocularis, occurs in geographically distinct strains that can be distinguished based on sequence variations of mitochondrial genes and nuclear microsatellite targets. this report finds that the human case of alveolar echinococcosis occurring in minnesota in 1977 was caused by the n2 haplotype described previously; the n2 haplotype is distinct from eu ...201525404078
genetic analysis of echinococcus multilocularis originating from a patient with alveolar echinococcosis occurring in minnesota in 1977.to date, only a single proven case of autochthonous human alveolar echinococcosis has been recorded in minnesota in 1977. at that time, echinococcal lesions removed from the patient were experimentally inoculated into voles, and the parasite materials obtained from the voles were preserved as histopathologic specimens for 30 years. in this study, retrospective genetic analysis of larval echinococcus multilocularis originating in the human case was performed using the histopathologic specimens. d ...200818689631
echinococcus multilocularis in peromyscus maniculatus and vulpes vulpes from minnesota. 19685757663
alveolar hydatid disease in minnesota. first human case acquired in the contiguous united states.a 56-year-old woman from southwestern minnesota underwent an extended left hepatic lobectomy to remove a large multinodular mass with a necrotic central cavity. the clinical, serological, and pathological findings led to the diagnosis of alveolar hydatid disease, and specific identification of echinococcus multilocularis was achieved by growing mature larvas in voles inoculated intraperitoneally with tissue from the hepatic lesions. the patient probably acquired her infection some years previous ...1979762867
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