| balamuthia mandrillaris, agent of amebic encephalitis: detection of serum antibodies and antigenic similarity of isolates by enzyme immunoassay. | we report the development of an enzyme-linked immunosorbent assay (elisa) for detecting antibodies to balamuthia mandrillaris, a free-living ameba that is an etiologic agent of granulomatous amebic encephalitis (gae). as part of the california encephalitis project (cep), we have tested serum and cerebrospinal fluid (csf) samples from a subgroup of 130 hospitalized encephalitis patients (out of approximately 430 samples) over a 16-month period. case criteria were based on clinical, laboratory, an ... | 2008 | 18681845 |