| seasonality and the requirements for perpetuation and eradication of viruses in populations. | perpetuation of a virus in a population is distinct from the ability to persist in a cell culture or individual host. parameters which determine perpetuation include: 1) the size of the population; 2) the turnover of the population; 3) the proportion of immunes in the population; 4) the transmissibility of the infection; and 5) the generation time between sequential infections. these parameters may be grouped into two composite factors which most directly affect transmission dynamics and perpetu ... | 1979 | 218446 |
| challenges in biodefense research and the role of us army veterinary pathologists. | for years the nation's development of medical countermeasures to biowarfare agents has primarily existed as the domain of the united states military, but it has taken on increased urgency in the last few years. the realization that the civilian population is also at risk from biological agents has resulted in the institution of new biodefense programs at a variety of nonmilitary organizations. usamriid, a long-time leader in the nation's biodefense effort, will soon be joined by other us governm ... | 2007 | 20088227 |
| vaccinia virus infections in martial arts gym, maryland, usa, 2008. | vaccinia virus is an orthopoxvirus used in the live vaccine against smallpox. vaccinia virus infections can be transmissible and can cause severe complications in those with weakened immune systems. we report on a cluster of 4 cases of vaccinia virus infection in maryland, usa, likely acquired at a martial arts gym. | 2011 | 21470473 |