| toxicity of adductor muscles from the purple hinge rock scallop (crassadoma gigantea) along the pacific coast of north america. | mouse bioassay results of rock scallops occasionally monitored by official agencies of british columbia, washington and california before and/or after algal blooms from 1980-1990 revealed that 24%, 38% and 87% of adductor muscles, whole body and viscera, respectively, were unsafe (greater than or equal to 80 micrograms saxitoxin equivalents/100 g tissue) for human consumption. the safety of adductor muscles could not be predicted from corresponding toxicity levels of the viscera but the absence ... | 1991 | 1926187 |
| carrier herbal medicine: an evaluation of the antimicrobial and anticancer activity in some frequently used remedies. | the antimicrobial properties of some traditional carrier herbal preparations were evaluated using an agar dilution method. pitch preparations were screened against known human pathogens: escherichia coli, staphylococcus aureus, pseudomonas aeruginosa, candida albicans and aspergillus fumigatus. the results indicated definite antimicrobial activity in the pitch preparations of picea glauca and pinus contorta and provide a starting point for pharmacognostic evaluation of these species. in addition ... | 1996 | 8771456 |
| toxoplasma gondii in vancouver island cougars (felis concolor vancouverensis): serology and oocyst shedding. | one of 12 necropsied cougars (felis concolor vancouverensis) from vancouver island, british columbia, canada, shed toxoplasma gondii oocysts confirmed by mouse bioassay. eleven of the 12 cougars (92%) had antibodies to t. gondii by the modified agglutination test with titers of <1:25 (1 cougar), 1:50 (8 cougars), and 1:500 (3 cougars). one additional cougar fecal sample collected from the victoria watershed environment also contained t. gondii oocysts. in 1995, the largest reported outbreak of h ... | 1998 | 9576522 |
| migratory songbirds disperse ticks across canada, and first isolation of the lyme disease spirochete, borrelia burgdorferi, from the avian tick, ixodes auritulus. | during a 3-yr comprehensive study, 196 ixodid ticks (9 species) were collected from 89 passerine birds (32 species) from 25 localities across canada to determine the distribution of avian-associated tick species and endogenous lyme disease spirochetes, borrelia burgdorferi johnson, schmid, hyde, steigerwalt, and brenner. we report the following first records of tick parasitism on avian hosts: the rabbit-associated tick, ixodes dentatus marx, from manitoba and ontario; the mouse tick, ixodes muri ... | 2005 | 17089744 |
| pions for radiotherapy at triumf. | beams of negative pi-mesons (pions) have depth-dose characteristics which are favorable for radiation therapy. as well, the densely ionizing radiations resulting from pion capture give pion beams an increased rbe and reduced oer, largely confined to the treatment volume. three facilities capable of testing pion beams for therapy now exist: triumf in vancouver, lampf in new mexico and sin in villigen, switzerland. patient treatment is already underway at lampf and will commence at triumf in novem ... | 1980 | 7364844 |
| bat rabies in canada 1963-1967. | six hundred and twenty-eight insectivorous bats originating from seven provinces were submitted to this institute for rabies diagnosis between august 1, 1963 and december 31, 1967. brain tissue was examined by the fluorescent antibody technique and the mouse infectivity test was carried out with brain, salivary gland, interscapular adipose tissue and kidney samples. rabies virus was detected in 44 bats, 29 of which were from ontario, 12 from british columbia and three from manitoba. most of the ... | 1969 | 4242773 |
| laboratory diagnosis of rabies in western canada (1968--1977). | the results of laboratory examination of 18,086 specimens for the presence of rabies antigen by the fluorescent antibody and mouse inoculation tests over a ten year period are presented. the submissions were received from british columbia, alberta, saskatchewan, the yukon and the northwest territories. of those examined, 10.74% were positive: however, the incidence of rabies varied widely in the specimens and species submitted, depending on their origin. the principal wildlife reservoirs of the ... | 1979 | 509378 |
| a decade of experience: cryptococcus gattii in british columbia. | it has been over a decade since cryptococcus gattii was first recognized as the causative organism of an outbreak of cryptococcosis on vancouver island, british columbia. a number of novel observations have been associated with the study of this emergent pathogen. a novel genotype of c. gattii, vgiia was described as the major genotype associated with clinical disease. minor genotypes, vgiib and vgi, are also responsible for disease in british columbians, in both human and animal populations. th ... | 2011 | 21960040 |
| a kcnq1 v205m missense mutation causes a high rate of long qt syndrome in a first nations community of northern british columbia: a community-based approach to understanding the impact. | hereditary long qt syndrome is named for a prolonged qt interval reflecting predisposition to ventricular arrhythmias and sudden death. a high rate in a remote, northern canadian first nations community was brought to attention. | 2008 | 18580685 |
| a survey for paralytic shellfish poisoning (psp) in vancouver harbour. | shellfish samples were collected from seven inter-tidal and two sub-tidal sites between 23 may and 8 june 1999 in vancouver harbour and were analysed for paralytic shellfish poisoning (psp) using a mouse bioassay. psp was detected in mussels collected at four sampling sites in english bay and burrard inlet, at a concentration below 20 microg saxitoxin equivalents (stxeq)/100 g wet weight. | 2004 | 12962651 |
| naturally occurring periodontal bone loss in the wild deer mouse, genus peromyscus. | historically, animal models for the study of periodontal diseases have incorporated surgically created defects, plaque retentive ligatures, as well as soft and high-sucrose diets which may not accurately reflect progression of the natural disease. spontaneous periodontal disease is seen in a few animal species, but these are often expensive to maintain and are unsuitable for manipulation using advanced molecular biology techniques. mice are inexpensive, easy to maintain, and are routinely used f ... | 2001 | 11394397 |