Publications

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primary and secondary dapsone resistance of m. leprae in martinique, guadeloupe, new caledonia, tahiti, senegal, and paris between 1980 and 1985.primary and secondary dapsone resistance were studied among lepromatous patients living in martinique, guadeloupe, new caledonia, tahiti, senegal, and paris. four hundred fifteen biopsies were taken from clinically active and bacteriologically positive (bacterial index greater than 2) patients in the 6-year period of 1980-1985. among these, 280 biopsies that contained 5 x 10(4) acid-fast bacilli per ml with a morphological index of at least 0.10 were inoculated into the mouse foot pad, and 229 h ...19873323369
ciguatera fish poisoning in the caribbean islands and western atlantic.ciguatera fish poisoning (ciguatera), a common poisoning caused by fish ingestion, is reviewed in the western atlantic and the caribbean waters. it is endemic from florida coasts (northern limit) to martinique island (southern limit), with outbreaks occurring from time to time. in the caribbean, ciguatera causes a polymorphic syndrome with gastrointestinal, cardiovascular, and neurological signs and symptoms. neurological and muscular dysfunctions can be treated by intravenous injection of d-man ...200112882228
thrombotic stroke following snake bites by the "fer-de-lance"bothrops lanceolatus in martinique despite antivenom treatment: a report of three recent cases.the severity of envenoming from bothrops lanceolatus is determined by the development of cerebral, myocardial or pulmonary infarctions, and occasionnaly by serious local envenoming. introduction of specific antivenom has resulted in a dramatic improvement in the prognosis of this envenoming. against this background, we report 3 recent cases of patients bitten by b. lanceolatus who developed cerebral infarctions despite early administration of antivenom.200616750232
snake venomics of the lesser antillean pit vipers bothrops caribbaeus and bothrops lanceolatus: correlation with toxicological activities and immunoreactivity of a heterologous antivenom.the venom proteomes of the snakes bothrops caribbaeus and bothrops lanceolatus, endemic to the lesser antillean islands of saint lucia and martinique, respectively, were characterized by reverse-phase hplc fractionation, followed by analysis of each chromatographic fraction by sds-page, n-terminal sequencing, maldi-tof mass fingerprinting, and collision-induced dissociation tandem mass spectrometry of tryptic peptides. the venoms contain proteins belonging to seven ( b. caribbaeus) and five ( b. ...200818785768
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