| voluntary intake of "tiquira", an alcoholic beverage prepared from fermented manioc, decreases immunoglobulin production and increases self-reactivity in mice. | we studied the effects of chronic voluntary ingestion of "tiquira" (50%)--an alcoholic beverage prepared from fermented manioc, widely consumed in maranhão,--on the natural immunological activity of young adult (2-3 months old) c57b1/6j mice (16-17 g) by evaluating the number of plaque-forming cells (pfcs) in the spleen and by titrating serum antibodies by elisa. voluntary ingestion of "tiquira" for 30 days decreased immunoglobulin secretion in serum (control: 1600 +/- 30 vs experimental: 193 +/ ... | 1992 | 1304941 |