Publications

a polymorphism in the amh type ii receptor gene is associated with age at menopause in interaction with parity.	anti-müllerian hormone (amh) inhibits primordial follicle recruitment in the mouse ovary. we hypothesize that in women amh signaling also regulates the usage of the primordial follicle pool and hence influences the onset of menopause. since age at menopause has a strong genetic component, we investigated the role of amh signaling using a candidate gene approach.	2007	17636279
on key lesions and all that: a tribute to paul lohman.	this paper is a tribute to paul lohman at the occasion of his retirement from the position of professor in the medical faculty at the leiden university in the netherlands and as director of its department of radiation genetics and chemical mutagenesis. paul's contributions to the science of genetic toxicology are discussed in the context of more recent insights as to how mammalian cells process dna damage, and how this may lead to cancer and, possibly, aging. starting with his work on the charac ...	2002	11827705