| primary and secondary dapsone resistance of m. leprae in martinique, guadeloupe, new caledonia, tahiti, senegal, and paris between 1980 and 1985. | primary and secondary dapsone resistance were studied among lepromatous patients living in martinique, guadeloupe, new caledonia, tahiti, senegal, and paris. four hundred fifteen biopsies were taken from clinically active and bacteriologically positive (bacterial index greater than 2) patients in the 6-year period of 1980-1985. among these, 280 biopsies that contained 5 x 10(4) acid-fast bacilli per ml with a morphological index of at least 0.10 were inoculated into the mouse foot pad, and 229 h ... | 1987 | 3323369 |
| prevalence and distribution of ret/ptc 1, 2, and 3 in papillary thyroid carcinoma in new caledonia and australia. | the world's highest incidence of thyroid cancer has been reported among females in new caledonia, a french overseas territory in the pacific located between australia and fiji. to date, no molecular genetic studies in this population are available. over the past few years, the oncogenic rearrangement of the ret protooncogene (ret/ptc) has been studied in papillary carcinomas in different populations. in this study, we investigated the prevalence and distribution of ret/ptc1, 2, and 3 in papillar ... | 2000 | 10946873 |
| detection of ciguatoxin-like and paralysing toxins in trichodesmium spp. from new caledonia lagoon. | marine pelagic cyanobacteria trichodesmium are widespread in the new caledonia lagoon. blooms of these oscillatoriales are suspected to be a potential source of toxins in the ciguatera food chain and were previously reported to contain certain types of paralysing toxins. in the present study, toxicity experiments were conducted on lipid- and water-soluble extracts of freeze-dried samples of these cyanobacteria. lipid-soluble fractions revealed a ciguatoxin-like activity in both in vivo (mouse bi ... | 2010 | 20638088 |
| experimental hamster infection with a strain of leptospira borgpetersenii ballum isolated from a reservoir mouse in new caledonia. | leptospirosis is a neglected zoonosis caused by pathogenic leptospira. in this study, we characterized the virulence of isolate b3-13s obtained from a wild mouse (mus musculus) captured in new caledonia, subsequently identified as a bacterium belonging to the l. borgpetersenii serogroup ballum. hamsters were infected with an intraperitoneal injection of 2 × 10(8) bacteria, resulting in severe histopathological organ damages consistent with tissue lesions previously observed with other strains. h ... | 2015 | 25758655 |