| immunogenicity of specific bordetella pertussis surface antigens in diphtheria-tetanus-pertussis (dtp) vaccines. | the predominant causative organism of whooping cough in australia is of a serotype which has normally been associated overseas with unvaccinated communities. australian dtp vaccines pass the statutory mouse test for bordetella pertussis potency but this test is now believed to be relatively insensitive to certain factors, especially the major type-specific agglutinogens, which are presumably also important in the human host-parasite relationship. because endemic b. bronchiseptica infections make ... | 1988 | 2897927 |
| a serologic survey for viruses and mycoplasma pulmonis among wild house mice (mus domesticus) in southeastern australia. | plasma samples from 267 wild house mice (mus domesticus) trapped at 14 sites in southeastern australia were screened for antibody to 14 viruses normally associated with laboratory-reared rodents and to mycoplasma pulmonis. serologic prevalence was high for murine cytomegalovirus (99%, n = 94), murine coronavirus (95%), and murine rotavirus (74%). samples from mice collected at all sites contained antibody to these viruses. the serologic prevalence was lower for mouse adenovirus, strain k87 (37%) ... | 1993 | 8487371 |
| spiders of medical importance in the asia-pacific: atracotoxin, latrotoxin and related spider neurotoxins. | 1. the spiders of medical importance in the asia-pacific region include widow (family theridiidae) and australian funnel-web spiders (subfamily atracinae). in addition, cupboard (family theridiidae) and australian mouse spiders (family actinopodidae) may contain neurotoxins responsible for serious systemic envenomation. fortunately, there appears to be extensive cross-reactivity of species-specific widow spider antivenom within the family theridiidae. moreover, sydney funnel-web antivenom has be ... | 2002 | 12165044 |
| aspects of the life history of muspicea borreli (nematoda: muspiceidae), parasite of the house mouse (mus domesticus) in australia. | prevalence of muspicea borreli (nematoda) infection in wild populations of mus domesticus in forests in southeastern new south wales and in rural canberra, australia was variable, relatively low and the parasite occurred predominantly in male mice. experimental infection of balb/c mice occurred only via subcutaneous inoculation but was achieved using i) adults containing embryonating eggs, ii) adults containing active larvae and iii) active larvae dissected from the uterus of female worms. exper ... | 2002 | 12375362 |
| nitrogen requirements and urea recycling in an omnivorous marsupial, the northern brown bandicoot isoodon macrourus. | the maintenance nitrogen (n) requirement of the northern brown bandicoot, isoodon macrourus, was determined by giving captive animals diets based on a commercial small carnivore mix and shredded sweet potato, with 20% sand included in the moist diet to simulate the soil ingested by bandicoots during natural foraging. linear regression of n balance on n intake yielded maintenance n requirements of 438 mg kg(-0.75) d(-1) on a dietary basis and 413 mg kg(-0.75) d(-1) on a truly digestible basis. th ... | 2005 | 15887092 |
| overexpression of lmo4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer. | the zinc finger protein lmo4 is overexpressed in a high proportion of breast carcinomas. here, we report that overexpression of a mouse mammary tumor virus (mmtv)-lmo4 transgene in the mouse mammary gland elicits hyperplasia and mammary intraepithelial neoplasia or adenosquamous carcinoma in two transgenic strains with a tumor latency of 13-18 months. to investigate cellular processes controlled by lmo4 and those that may be deregulated during oncogenesis, we used rna interference. down-regulati ... | 2005 | 15897450 |
| prevalence of mouse mammary tumor virus (mmtv) in wild house mice (mus musculis) in southeastern australia. | we determined the prevalence of mouse mammary tumor virus (mmtv) in introduced, free-roaming, wild house mice (mus musculus domesticus) [corrected] and compared envelope (env) and long terminal repeat (ltr) nucleotide sequences of viruses from wild mice and other sources. mice were trapped on two occasions, in october (spring) and the following may (autumn) of 2003-2004 in the mallee region of northwestern victoria, australia. animals were assigned to three cohorts (subadult, young, and old adul ... | 2007 | 17984262 |
| why is alpha-actinin-3 deficiency so common in the general population? the evolution of athletic performance. | 'we can now explain how this common genetic variation influences athletic performance as well as why it has become so common in the general population. there is a fascinating link between factors that influence survival in ancient humans and the factors that contribute to athletic abilities in modern man.' the human actn3 gene encodes the protein alpha-actinin-3, a component of the contractile apparatus in fast skeletal muscle fibers. in 1999, we identified a common polymorphism in actn3 (r577x) ... | 2008 | 18637739 |
| japanese encephalitis - prevention in travellers. | this article is the fourth in a series providing a summary of prevention strategies and vaccination for infections that may be acquired by travellers. the series aims to provide practical strategies to assist general practitioners in giving travel advice, as a synthesis of multiple information sources which must otherwise be consulted. japanese encephalitis (je) is a potentially fatal arboviral infection prevalent in large parts of asia, as well as papua new guinea and the outer torres strait is ... | 2010 | 20628677 |