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a blue-green alga from okinawa contains aplysiatoxins, the third class of tumor promoters.the causative agents of swimmer's itch were isolated from the marine blue-green alga, lyngbya majuscula, which grows off the coast of the okinawa islands, japan. nuclear magnetic resonance and mass spectral studies revealed that these agents were identical with aplysiatoxin and debromoaplysiatoxin, which were previously shown to be the causative agents of swimmer's itch in hawaii. aplysiatoxin and debromoaplysiatoxin were recently found to be potent tumor promoters in two-stage carcinogenesis in ...19853924698
first records of tick-borne pathogens, borrelia, and spotted fever group rickettsiae in okinawajima island, japan.in early april 2000, tick-borne pathogens were surveyed in the northern area of okinawajima island, okinawa prefecture, which is the southernmost area of japan. borrelia valaisiana, a lyme disease spirochete, was isolated from a field mouse mus calori, and unidentified rickettsiae of the spotted fever group were isolated from all stages of amblyomma testudinarium. these are the first reports of these pathogens on okinawajima island.200111293483
amino acid sequence of a basic aspartate-49-phospholipase a2 from trimeresurus flavoviridis venom and phylogenetic analysis of crotalinae venom phospholipases a2.trimeresurus flavoviridis snakes inhabit the southwestern islands of japan: amami-oshima, tokunoshima and okinawa. a phospholipase a2 (pla2) of basic nature (pi 8.5) was isolated from the venom of amami-oshima t. flavoviridis. its amino acid sequence determined by the ordinary procedures was completely in accord with that predicted from the nucleotide sequence of the cdna previously cloned from amami-oshima t. flavoviridis venom gland, which was named pla-b'. it consists of 122 amino acid residu ...200515972222
ciguatera incidence and fish toxicity in okinawa, japan.okinawa being located in the subtropical region has the highest incidence of ciguatera in japan. officially, 33 outbreaks involving 103 patients have been reported between 1997 and 2006. the implicated species were variola louti, lutjanus bohar, lutjanus monostigma, epinephelus fuscoguttatus, unidentified lutjanus sp., plectropomus areolatus, oplegnathus punctatus, epinephelus polyphekadion, caranx ignobilis and moray eel. toxicities of the leftover meals, as determined by mouse bioassays, range ...201019520098
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