| [the causative agent from a patient with spotted fever group rickettsiosis in japan on awaji island, hyogo]. | misaka strain was isolated as the causative agent from a patient with spotted fever group rickettsiosis in japan by using nude mice on awaji island, hyogo in september 1988. the nude mice infected with the isolate showed weakness and splenomegaly and died in two or three weeks after the infection. the cyclophosphamide-treated mice infected with the isolate died between four and seven days after the infection. the infected normal mice recovered and acquired immunity. the infected adult male guine ... | 1990 | 2205668 |
| first isolation of a rickettsia closely related to japanese spotted fever pathogen from a tick in japan. | in may 1993, we collected unfed ticks in anan, tokushima prefecture, shikoku district, japan, a highly endemic area of japanese spotted fever (jsf). we isolated jsf rickettsiae from these ticks by inoculating tick-emulsions into l-929 cells. of the four genera and seven species of ticks examined, only one larva of dermacentor taiwanensis sugimoto yielded a rickettsial isolate. the isolate (dt-1 strain) was found to belong to the serotype common to the causative agent of jsf. this was based on it ... | 1994 | 8189407 |
| ostreopsis sp., a possible origin of palytoxin (ptx) in parrotfish scarus ovifrons. | a clone of toxic dinoflagellate ostreopsis sp. and six specimens of a parrotfish scarus ovifrons were collected in october 1997 at tokushima prefecture, japan. ostreopsis sp. was cultured in esm medium for 16 days, and after rearing the cell pellet (about 4.0x10(5) cells) was extracted with 50% methanol, partitioned between an aqueous layer and 1-butanol layer, and biochemically tested. similarly, the crude toxin from s. ovifrons was extracted, and tested. the mice injected with each 1-butanol l ... | 2003 | 12893058 |