| characteristics of different isolates of schistosoma japonicum from china in the final hosts. | the present paper deals with the susceptibility of common laboratory animals, such as mouse, rat, hamster, jird, rabbit and rhesus monkey, to infection with different isolates of schistosoma japonicum in the mainland of china under laboratory conditions. with the exception of the rat, all the animals under study were permissive hosts for different isolates though their worm recovery rates varied. the mean body length of pair-worms of the yunnan isolate was considerably smaller than that of the a ... | 1991 | 1948285 |
| phylogeography of chinese house mice (mus musculus musculus/castaneus): distribution, routes of colonization and geographic regions of hybridization. | house mice (mus musculus) are human commensals and have served as a primary model in biomedical, ecological and evolutionary research. although there is detailed knowledge of the biogeography of house mice in europe, little is known of the history of house mice in china, despite the fact that china encompasses an enormous portion of their range. in the present study, 535 house mice caught from 29 localities in china were studied by sequencing the mitochondrial d-loop and genotyping 10 nuclear mi ... | 2014 | 25065953 |
| reassortant h9n2 influenza viruses containing h5n1-like pb1 genes isolated from black-billed magpies in southern china. | h9n2 influenza a viruses have become endemic in different types of terrestrial poultry and wild birds in asia, and are occasionally transmitted to humans and pigs. to evaluate the role of black-billed magpies (pica pica) in the evolution of influenza a virus, we conducted two epidemic surveys on avian influenza viruses in wild black-billed magpies in guangxi, china in 2005 and characterized three isolated black-billed magpie h9n2 viruses (bbm viruses). phylogenetic analysis indicated that three ... | 2011 | 21980538 |
| mdm2 promoter snp309 is associated with risk of occurrence and advanced lymph node metastasis of nasopharyngeal carcinoma in chinese population. | mouse double minute 2 (mdm2) is a key negative regulator of the p53 activity. recently, a polymorphism in the mdm2 intronic promoter, snp309, was shown to influence mdm2 expression and p53 activity. we examined whether the snp309 was related to the risk of developing nasopharyngeal carcinoma (npc) among chinese populations. | 2007 | 17473193 |
| molecular basis of replication of duck h5n1 influenza viruses in a mammalian mouse model. | we recently analyzed a series of h5n1 viruses isolated from healthy ducks in southern china since 1999 and found that these viruses had progressively acquired the ability to replicate and cause disease in mice. in the present study, we explored the genetic basis of this change in host range by comparing two of the viruses that are genetically similar but differ in their ability to infect mice and have different pathogenicity in mice. a/duck/guangxi/22/2001 (dkgx/22) is nonpathogenic in mice, whe ... | 2005 | 16140781 |
| mutations clustered in exon 5 of the p53 gene in primary nasopharyngeal carcinomas from southeastern asia. | mutations in the p53 tumor suppressor gene play an important role in the development of many common human malignancies. in nasopharyngeal carcinomas (npc), p53 gene mutations were not detected in primary tumors, with one exception for a primary tumor displaying a p53 mutation at codon 280, whereas p53 mutations were identified in some metastatic and nude mouse-passaged npc specimens. in the present report, 41 npc primary tumors of the undifferentiated carcinoma nasopharyngeal type (ucnt; 21 from ... | 1995 | 7729941 |