partial structural determination of hepatotoxic peptides from microcystis aeruginosa (cyanobacterium) collected in ponds of central china. | waterbloom samples of the colonial cyanobacterium microcystis aeruginosa, collected in fish ponds at the hydrobiological institute, wuhan, people's republic of china, were hepatotoxic to mice. lyophilized cells had an ld50 (i.p. mouse; 40 mg/kg) and signs of poisoning similar to that reported for other cyanobacterial hepatotoxic peptides. two toxins, with an ld50 (i.p. mouse) of 40 and 150 micrograms/kg, were isolated using gel filtration and high performance liquid chromatography. the amino aci ... | 1988 | 3149051 |
sensitivity of different isolates of schistosoma japonicum from china to praziquantel. | groups of c57bl inbred mice infected with each of the 4 different isolates, (anhui, hubei, sichuan and yunnan) of schistosoma japonicum from the mainland of china were treated with praziquantel (pzq) and the parasiticidal effects were compared. worm reduction rate was recorded to assess systematically the sensitivity of 4 different isolates to pzq in the mouse. three dosage-levels of pzq, ie 150, 230 and 310 mg/kg body weight in single doses were used. the worm development rates of control group ... | 1992 | 1439978 |
characteristics of different isolates of schistosoma japonicum from china in the final hosts. | the present paper deals with the susceptibility of common laboratory animals, such as mouse, rat, hamster, jird, rabbit and rhesus monkey, to infection with different isolates of schistosoma japonicum in the mainland of china under laboratory conditions. with the exception of the rat, all the animals under study were permissive hosts for different isolates though their worm recovery rates varied. the mean body length of pair-worms of the yunnan isolate was considerably smaller than that of the a ... | 1991 | 1948285 |
[evaluation of prevalent status of kala-azar in endemic area of hubei province]. | to identify the diagnosis of 14 cases with "kala-azar" previously reported in hubei province since 1989 and to evaluate the present status of the disease. | 2000 | 12567700 |
molecular and antigenic characterization of hv114, a hantavirus isolated from a patient with haemorrhagic fever with renal syndrome in china. | the relationship of a hantaan-like virus (hv114), isolated from a patient with haemorrhagic fever with renal syndrome in hubei province, people's republic of china, to other pathogenic hantaviruses was evaluated by cross-neutralization studies and nucleotide sequence analysis of the m genome segment. plaque reduction neutralization assays indicated that hv114 is closely related to prototype hantaan (htn) virus, strain 76-118, which was originally isolated from an apodemus field mouse in korea. c ... | 1993 | 8102176 |