| prevention of sporogony of plasmodium vivax in anopheles dirus mosquitoes by transmission-blocking antimalarials. | the sporontocidal activity of four dihydroacridine-diones (wr-233602, wr-243251, wr-250547, and wr-250548) and three fluoroquinolones (wr-279135, wr-279298, and wr-279288) was determined against naturally circulating isolates of plasmodium vivax. laboratory-reared anopheles dirus mosquitoes were infected with p. vivax by feeding them on gametocytemic volunteers reporting to local malaria clinics in kanchanaburi and tak provinces, thailand. four days after the infectious feed, mosquitoes were re- ... | 2001 | 11561707 |