| [in vitro effects of antiviral drugs on the reproduction of highly pathogenic influenza a/h5n1 virus strains that induce epizooty among poultry in the summer of 2005]. | commercial drugs, such as rimantadine, amantadine, rivabirine, and arbidole, are effective in suppressing the in vitro reproduction of highly pathogenic avian influenza a/h5n1 viruses. the study has used a porcine embryonic renal cell line and the highly pathogenic a/duck/novosibirsk/56/05 (h5n1) strain from a sick domestic duck (anas platyrhynchos domesticus) (chany lake environs, novosibirsk region). | 2006 | 16756173 |
| [molecular genetic analysis of the biological properties of highly pathogenic influenza a/h5n1 virus strains isolated from wild birds and poultry during epizooty in western siberia (july 2005)]. | the full-size genomes of 2 highly pathogenetic avian influenza (hpai) virus strains isolated from a wild great-crested grebe (a/grebe/novosibirsk/29/05) and a domestic duck (a/duck/novosibirsk/56/05) in the tract of the chany hollow, barabino forest-steppe (novosibirsk region) during the epizootic outbreak in the summer of 2005. the reproductive properties of these strains successively increase in the series of cell lines bhk-2 --> leh --> vero-e6 --> mdck --> ps. a/grebe/novosibirsk/29/05 and a ... | 2006 | 16756172 |
| [isolation of influenza a/h5n1 virus strains from poultry and wild birds in west siberia during epizooty (july 2005) and their depositing to the state collection of viruses (august 8, 2005)]. | six strains of influenza ah5n1 virus were isolated, by using ps and mdck continuous cell lines from poultry and wild birds, which were collected on july 28, 2005 in the samples taken from 5 examines species of wild birds in the novosibirsk region during the epizootic outbreak with a high mortality. the strains were identified by means of hit, rt-pcr, and microchip-based techniques. two strains, a/grebe/novosibirsk/29/05 (h5n1) and a/duck/novosibirsk/56/05 (h5n1), were deposited to the russian st ... | 2006 | 16515035 |
| antigenic epitopes in the hemagglutinin of qinghai-type influenza h5n1 virus. | the highly pathogenic avian influenza h5n1 viruses have become widespread and evolved into several clades. in our previous studies, the antigenic sites of the h5 hemagglutinin (ha) were characterized by selection and sequencing of escape mutants. in the present studies we analyzed the antigenic epitopes recognized by monoclonal antibodies against avian influenza a/duck/novosibirsk/56/05 (h5n1) virus isolated in western siberia and belonging to subclade 2.2 of the h5n1 viruses. the analysis revea ... | 2010 | 20373998 |