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nucleotide sequence of the envelope glycoprotein gene of a dengue-2 virus isolated during an epidemic of benign dengue fever in tonga in 1974. 19902216784
plasma levels of tumour necrosis factor alpha and transforming growth factor beta-1 in children with dengue 2 virus infection in french polynesia.the pathogenesis of dengue haemorrhagic fever (dhf) is not well understood. in the absence of predictive clinical or biological criteria, the management of dhf patients remains difficult. the role played by cytokines in the occurrence of dhf has been suggested by several authors. in this study, we determined the plasma levels of tumour necrosis factor alpha (tnf alpha) and transforming growth factor beta-1 (tgf beta-1) in 52 children with laboratory-confirmed dengue virus infection admitted to h ...199810326113
[the specific epidemiological surveillance of dengue: the method and its importance since the dengue-2 epidemic in french polynesia in 1996].dengue fever is present in tropical and subtropical regions and its geographical extension and the simultaneous increase of its mortality are worrisome. in endemic or epidemic countries, the aim of dengue-specific epidemiological surveillance is to confirm as soon as possible the circulation of a new viral dengue serotype, i.e. the beginning of an epidemic. the efficiency of the control strategy is improved by an earlier epidemic alert. in french polynesia, dengue-3 virus circulated since 1989 a ...19989705191
changing clinical and biological manifestations of dengue during the dengue-2 epidemic in french polynesia in 1996/97--description and analysis in a prospective study.in august 1996 dengue-2 virus was detected in french polynesia for the first time since 1976. a prospective study was conducted from november 1996 to april 1997. each time one of 7 physicians suspected dengue, the patient was enrolled and epidemiological, clinical and biological data were recorded. dengue diagnosis was confirmed by virus isolation and igm detection. the aims of this study were to find clinical and biological predictive factors constituting a specific profile of dengue (df) and d ...19989855396
natural attenuation of dengue virus type-2 after a series of island outbreaks: a retrospective phylogenetic study of events in the south pacific three decades ago.dengue is an expanding arboviral disease of variable severity characterized by the emergence of virus strains with greater fitness, epidemic potential and possibly virulence. to investigate the role of dengue virus (denv) strain variation on epidemic activity we studied denv-2 viruses from a series of south pacific islands experiencing outbreaks of varying intensity and clinical severity. initially appearing in 1971 in tahiti and fiji, the virus was responsible for subsequent epidemics in americ ...201020663532
aedes aegypti in tahiti and moorea (french polynesia): isoenzyme differentiation in the mosquito population according to human population density.genetic differences at five polymorphic isoenzyme loci were analyzed by starch gel electrophoresis for 28 aedes aegypti samples. considerable (i.e., high fst values) and significant (i.e., p values >10(-4)) geographic differences were found. differences in ae. aegypti genetic structure were related to human population densities and to particularities in mosquito ecotopes in both tahiti and moorea islands. in highly urbanized areas (i.e., the papeete agglomeration), mosquitoes were highly structu ...200010813476
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