Publications

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chloroquine-resistant plasmodium falciparum from east africa: cultivation and drug sensitivity of the tanzanian i/cdc strain from an american tourist.a strain of plasmodium falciparum, designated tanzanian i/cdc, from an american tourist returning from tanzania, was isolated in vitro and in the aotus monkey. clinically, the infection showed a late recrudescent pattern of chloroquine resistance. in 2 inoculated aotus monkeys, the infection recrudesced after a dose of chloroquine (40 mg/kg) curative for sensitive p. falciparum strains in the aotus monkey. in 4 ,dditional monkeys two primary infections and one of the recrudescent parasitaemias w ...197991887
letter: research with plasmodium falciparum in volunteers. 19744606749
a retrospective examination of sporozoite- and trophozoite-induced infections with plasmodium falciparum: development of parasitologic and clinical immunity during primary infection.a retrospective analysis was made of the parasitologic and fever records of 318 patients who had been infected with the el limon, santee cooper, or mclendon strains of plasmodium falciparum for treatment of neurosyphilis between 1940 and 1963 to determine the development of parasitologic and clinical immunity during primary infection. the presence of fever > or = 101 degrees f and > or = 104 degrees f, asexual parasite counts > or = 1,000 and > or = 10,000/microl, and gametocyte counts > or = 10 ...199910432041
evaluation of the pyrogenic threshold for plasmodium falciparum malaria in naive individuals.a retrospective statistical analysis of two independent data sets was undertaken to determine the peripheral plasmodium falciparum parasitemia associated with the onset of fever in naive human hosts, and to assess the dynamics of this threshold during the course of the infection and subsequent reinfection. analysis indicated that there were significant differences between the thresholds for different p. falciparum strains in one data set, and significant interactions between host ethnicity and p ...200212201578
imported malaria at an inner-city hospital in the united states.more than 1000 cases of malaria are reported to the centers for disease control and prevention each year among travelers or immigrants.200515654173
hepatitis temporally associated with an herbal supplement containing artemisinin - washington, 2008.artemisinins are a class of compounds that include artesunate, artemether, and artemisinin and have potent antimalarial activity. in combination with other drugs (artemisinin combination therapy), these compounds are the first-line treatment recommended by the world health organization for plasmodium falciparum infections. artemisinins have been available in the united states without a prescription as herbal supplements for at least 10 years; these supplements are marketed for general health mai ...200919680221
pediatric malaria: 8-year case series in atlanta, georgia, and review of the literature.although malaria is frequent in travelers, it is often misdiagnosed on initial presentation, especially in children. the objective of this study is to describe epidemiology, clinical and laboratory presentation, and treatment of children with malaria in the united states.201020920055
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