| malaria in northern ireland. | the clinical features, parasitology and prophylactic history of 67 patients who imported malaria to northern ireland between 1974 and 1983 are reported. p. falciparum infections were encountered more frequently than anticipated from current united kingdom experience. the clinical implications of these findings are discussed. | 1986 | 3526691 |
| information about antimalarial chemoprophylaxis in hospitalised patients--is it adequate? | malaria remains a huge public health problem worldwide, with over 100 million new cases annually, causing one to two million deaths. this global problem spills over into the uk, with around 2000 cases of reported annually. the proportion of infections due to plasmodium falciparum (pf) continues to increase and worse still accounts for five to 12 deaths per year. in 1992, nathwani et al reported the 10 year experience of malaria cases admitted to the regional infection unit, in aberdeen, scotland ... | 1997 | 9226772 |
| changes in cytokine production associated with acquired immunity to plasmodium falciparum malaria. | individuals living in malaria-endemic areas eventually develop clinical immunity to plasmodium falciparum. that is, they are able to limit blood parasite densities to extremely low levels and fail to show symptoms of infection. as the clinical symptoms of malaria infection are mediated in part by pro-inflammatory cytokines it is not clear whether the acquisition of clinical immunity is due simply to the development of antiparasitic mechanisms or whether the ability to regulate inflammatory cytok ... | 2001 | 11737069 |