| respiratory syncytial virus laboratory surveillance and hospitalization trends in south texas. | surveillance of seasonal variations in respiratory syncytial virus (rsv) outbreaks is an important component in clinical decision-making. a retrospective analysis of 11 years of laboratory-based rsv surveillance and 7 years of hospitalization data was carried out to better define the onset and duration of the rsv season in south texas, as well as to evaluate the clinical impact and timing of rsv outbreaks on the number of infants hospitalized with rsv infection. all but one of the seasons examin ... | 2007 | 18090201 |
| encephalopathy associated with respiratory syncytial virus bronchiolitis. | respiratory syncytial virus is an extremely common cause of childhood respiratory infections resulting in significant morbidity and mortality. although apnea is a well-known complication in young infants with respiratory syncytial virus bronchiolitis, the encephalopathy associated with this infection is not well recognized. our study reveals an incidence of encephalopathy of 1.8% in a total of 487 patients with respiratory syncytial virus bronchiolitis studied over a period of almost 4 years. se ... | 2001 | 11292214 |
| gene sequence variability of the three surface proteins of human respiratory syncytial virus (hrsv) in texas. | human respiratory syncytial virus (hrsv) has three surface glycoproteins: small hydrophobic (sh), attachment (g) and fusion (f), encoded by three consecutive genes (sh-g-f). a 270-nt fragment of the g gene is used to genotype hrsv isolates. this study genotyped and investigated the variability of the gene and amino acid sequences of the three surface proteins of hrsv strains collected from 1987 to 2005 from one center. sixty original clinical isolates and 5 prototype strains were analyzed. seque ... | 2014 | 24625544 |
| antigenic diversity of respiratory syncytial virus subgroup b strains circulating during a community outbreak of infection. | the epidemiological characteristics and relationship between respiratory syncytial virus (rsv) subgroup and virulence during an outbreak of rsv infection occurring in southeast texas in the winter season 1991/92 are described. fifty-two infants and children were diagnosed with rsv infection by rapid viral antigen detection and/or viral isolation. subgrouping of the isolates was carried out using 11-monoclonal anti-bodies. ten isolates were found to be subgroup b, and 8 isolates were subgroup a. ... | 1994 | 8046428 |
| hla-restricted cd8+ cytotoxic t lymphocyte, interferon-gamma, and interleukin-4 responses to respiratory syncytial virus infection in infants and children. | cd8+ cytotoxic t lymphocyte (ctl) activity, interferon (ifn)-gamma, and interleukin (il)-4 production were evaluated in a blinded manner among respiratory syncytial virus (rsv)-infected newborns and their mothers for 3 epidemic seasons. most mothers (80%) exhibited rsv-specific cd8+ ctl activity. twenty (80%) of the 26 infants exhibited significant rsv-specific ctl activity during or after their first rsv season. ctl frequency increased with rsv infection rate, reaching 75% by the end of the thi ... | 2001 | 11181144 |