| chlamydial infection and spatial ascension of the female genital tract: a novel hybrid cellular automata and continuum mathematical model. | sexually transmitted chlamydial infection initially establishes in the endocervix in females, but if the infection ascends the genital tract, significant disease, including infertility, can result. many of the mechanisms associated with chlamydial infection kinetics and disease ascension are unknown. we attempt to elucidate some of these processes by developing a novel mathematical model, using a cellular automata-partial differential equation model. we matched our model outputs to experimental ... | 2009 | 19735471 |
| radiobiology of the skin: review of some effects on epidermis and hair. | significant doses of ionizing radiation produce an acute skin reaction characterized by erythema, epilation, and dry or moist desquamation with or without erosions. these early acute changes are dose-dependent and reflect damage to the germinative cells of the epidermis and to the cutaneous vasculature. studies in the pig, for example, have shown that the degenerative phase of cell loss (2-3 weeks) results from reproductive failure in germinative cells and a sharp reduction in the proliferation ... | 1981 | 7252246 |
| work and contraction curves of atrial muscle preparations during anoxia and reoxygenation influenced by cardio-tonic and cardio-depressive drugs. | auxotonic work/beat and contraction curves were recorded from left guinea pig atria stimulated with 0.5 hz at 5 mn preload in k.h.-solution + 15 mmol/l glucose, 95% o2 or n2 + 5% co2, 30 degrees c. eight common parameters of the contraction curve were calculated simultaneously in a computerized system as reported previously (englert, r. et al., n.-arch. of pharmacol., 337, suppl. r. 60, 1988). by increased anaerobic glycolysis anoxia reduced contractile activity which after 30 min reached a plat ... | 1991 | 2021867 |
| molecules involved in sperm-oviduct adhesion and release. | in mammals, sperm ascension within the female reproductive tract involves a transient adhesion to the caudal isthmus of the oviduct. sperm adhesion to this specialized region, which is termed the "oviductal reservoir", extends the sperm fertile life span by delaying capacitation until, around ovulation, specific signals induce sperm release. in vivo and in vitro studies demonstrated that carbohydrates on the oviductal cell apical membranes and lectin-like molecules on the rostral sperm surface a ... | 2010 | 19682733 |