Publications

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balantidiasis outbreak in truk. 19734684887
cats, rats, and toxoplasmosis on a small pacific island. 19725063197
outbreak of japanese encephalitis on the island of saipan, 1990.during october 1990, an outbreak of encephalitis occurred on saipan. although no virus was isolated, patients seroconverted to japanese encephalitis (je) virus, indicating the first known occurrence of je on us territory since 1947. ten cases occurred among a population of 40,000. the prevalence of antibody to je virus among 234 lifelong saipan residents surveyed after the outbreak was 4.2%. age, household crowding, and lack of air conditioning were risk factors for infection. the seroprevalence ...19938387561
survey for selected pathogens in wild pigs (sus scrofa) from guam, marianna islands, usa.pigs (sus scrofa) were introduced to guam in the 1600's and are now present in high densities throughout the island. wild pigs are reservoirs for pathogens of concern to domestic animals and humans. exposure to porcine parvovirus, transmissible gastroenteritis, and leptospira interrogans has been documented in domestic swine but data from wild pigs are lacking. the close proximity of humans, domestic animals, and wild pigs, combined with the liberal hunting of wild pigs, results in frequent oppo ...201728622856
japanese encephalitis on saipan: a survey of suspected mosquito vectors.an outbreak of japanese encephalitis (je) occurred on saipan, commonwealth of northern mariana islands, in october 1990. adult and larval mosquitoes were collected during september-october 1991 to retrospectively determine the probable mosquito vector(s). virus was not isolated from 119 mosquito pools composed of 7,250 adult specimens as follows: aedes vexans nocturnis (14%), culex tritaeniorhynchus (39%), cx. sitiens group (11%), culex (culex) species (35%), and < 1% each of ae. albopictus, ae. ...19938386909
serologic and epidemiologic observations on toxoplasmosis on three pacific atolls. 19695817004
virus of the 1918 influenza pandemic era: new evidence about its antigenic character.in serums of unusually isolated pacific islanders whose only exposure to influenza occurred during the era of the 1918 pandemic the residual neutralizing antibody was greatest to the pr/8 and bh strains of human type a influenza virus, significantly lower to swine influenza virus, and absent to equine or later human type a virus strains. the pandemic virus was thus antigenically closer to human type a strains isolated during the middle 1930's than to other known influenza virus types.19694897391
trichinella infection in travelers.to define the incidence of trichinosis associated with foreign travel and characterize the epidemiologic and clinical features of cases acquired abroad, all case report forms submitted to the centers for disease control through state health departments and the national morbidity reporting system from 1975 to 1989 were reviewed. twenty-six cases of travel-associated trichinosis were identified during that period. most reported cases (73%) occurred between 1982 and 1987. affected patients were mor ...19911940453
guam's influenza epidemic(s) of 2009.to characterize syndromic and laboratory surveillance for influenza on guam during 2009, including the relation of cases to the timing of swine flu-related stories published in a local newspaper.201020540003
lyngbyastatins 8-10, elastase inhibitors with cyclic depsipeptide scaffolds isolated from the marine cyanobacterium lyngbya semiplena.investigation of an extract from the marine cyanobacterium lyngbya semiplena, collected in tumon bay, guam, led to the identification of three new cyclodepsipeptides, lyngbyastatins 8-10 (1-3). the structures of 1-3 were determined by nmr, ms, esims fragmentation and chemical degradation. compounds 1-3 are closely related to lyngbyastatins 4-7. like the latter compounds, we found 1-3 to inhibit porcine pancreatic elastase, with ic(50) values of 123 nm, 210 nm and 120 nm, respectively.200920098596
beyond guam: the cyanobacteria/bmaa hypothesis of the cause of als and other neurodegenerative diseases.excitement about neurogenetics in the last two decades has diverted attention from environmental causes of sporadic als. fifty years ago endemic foci of als with a frequency one hundred times that in the rest of the world attracted attention since they offered the possibility of finding the cause for non-endemic als throughout the world. research on guam suggested that als, parkinson's disease and dementia (the als/pdc complex) was due to a neurotoxic non-protein amino acid, beta-methylamino-l-a ...200919929726
risk assessment of an acetaminophen baiting program for chemical control of brown tree snakes on guam: evaluation of baits, snake residues, and potential primary and secondary hazards.the brown tree snake (boiga irregularis) is a significant ecological, agricultural, and economic pest on guam. acetaminophen has recently been identified as a promising snake toxicant. subsequent experimentation has shown that acetaminophen-mouse baits are readily consumed by and acutely toxic to browntree snakes. before implementing an island-wide acetaminophen-mouse baiting program for the reducton of brown tree snake populations,the potential risks to nontarget wildlife must be evaluated. qua ...200212322757
elisa antibodies to cysticerci of taenia solium in human populations in new guinea, oceania, and southeast asia.the presence of elisa antibodies to cysticerci of taenia solium was surveyed in populations of new guinea, micronesia, and several areas of southeast asia. it is confirmed that cysticercosis in new guinea remains limited to the primary wissel lakes focus in irian jaya, where the disease was introduced by the importation of infected pigs, and that it has not spread to populations east or south of the wissel lakes, or to papua new guinea. on the island of bali, indonesia, 21% of sera were positive ...19816211771
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