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[specific prevention of epidemic parotitis with live sofia-6 strain virus]. 19724673662
vaccinoprophylaxis of mumps using mumps vaccine, strain sofia 6, in bulgaria.a mumps vaccine, using strain sofia 6 prepared in guinea-pig kidney primary cell cultures, was gradually introduced in bulgaria to vaccinate 1- to 12-year-old children between 1972 and 1976. it was included in the national vaccine programme in 1977. the vaccine showed a slight reactogenicity, a good immunogenicity and a high epidemiological efficacy. due to the increased morbidity of mumps, revaccination was carried out in 4- to 12-year-old children in 1982. a high level of side-effects, mainly ...19947856287
characteristics of virulence signs of enteroinvasive escherichia coli (eiec) isolated in csfr and bulgaria in 1988-1990.during 1988-1990 a total of 345 virulent and avirulent strains of enteroinvasive e. coli (eiec) were isolated from human faeces in microbiological laboratories in prague and sofia. this group of strains belonged to a total of 11 serotypes. the most frequently encountered serotypes in both laboratories were: 0124, 0164 and 028ac. from patients 205 strains were obtained and from healthy subjects 140 strains of eiec. in all strains the following signs of virulence were investigated: biochemical pro ...19947812251
[incidence, diagnosis, prevention and treatment of insulin allergy].in the scientific institute for endocrinology, geriatrics and gerontology, sofia, 1723 diabetic patients were treated with insulin during the last 3 years. in 150 of them insulin allergy was supposed. the patients sensitivity toward the various insulin preparations was determined by intradermal test. insulin allergy was found in 29 patients (1.68%). insulin allergy was found more frequently in patients using acid insulin preparations and by frequent changes of the type of preparation. it is reco ...19883046141
[a hygienic study of new raw materials for cosmetic agents and household chemical preparations].studies are performed on the new bulgarian raw materials "aminookis" (ao) and "dezodorirashch agent" (da) the plants "alen mak"--plovdiv and "hyaluron"--sofia. chemical, toxicological and microbiological studies are carried out. thin-layer chromatographic and spectrophotometric methods for determination of ao, hyaluronic acid and da are developed and chemical studies on cosmetics, prepared with them, are carried out. during the repetition of a 21-day experiment on guinea pigs the threshold irrit ...19902099460
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