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respiratory viral infection in childhood. a survey in general practice, roehampton 1967-1972.the role of viruses and m. pneumoniae in episodes of acute respiratory illness in childhood has been studied in a london general practice. the total isolation rate was 31-7 per cent, but the rate varied from 32-6 per cent in upper respiratory infections to 64-0 per cent in pneumonia. the clinical features associated with infection were influenced not only by the type of agent but also by age and other host factors in infected children. rhinoviruses were more commonly isolated than any other agen ...1975164499
the treatment of mycoplasma pneumoniae infections. 1977601554
surveillance of mycoplasma pneumoniae infections in scotland 1986-1991.mycoplasma pneumoniae is the second most common cause of community-acquired pneumonia. infection is found worldwide and epidemics are said to occur in 4-yearly cycles. in scotland this pattern has been noted since 1982 and, in common with england and wales as well probably as other parts of europe, there is a current epidemic which began in the autumn of 1990. the disease has been noted predominantly in children and young adults, with lower respiratory tract infection as the most common manifest ...19921431178
acute respiratory infections. 19911669902
detection of mycoplasma genitalium in the genitourinary tract of women by the polymerase chain reaction.a polymerase chain reaction (pcr) was used to demonstrate the presence or absence of mycoplasma genitalium in the lower genital tract of 57 women who attended a sexually transmitted diseases clinic. the mycoplasma was detected in the cervix of 10 (17.5%) women and also in the vagina of 4 (16%) and the urethra of 6 (24%) of 25 women from whom multiple samples were obtained. chlamydia trachomatis was detected also by a pcr in 9 (16%) of the women, but only 3 were chlamydia-positive and mycoplasma- ...19911911958
a prospective study of viral and mycoplasma infections in chronic inflammatory bowel disease.seventy-two children with chronic inflammatory bowel disease were investigated for infections with various viruses and mycoplasma pneumoniae, chlamydia psittaci, and coxiella burnetii to determine whether these pathogens are associated with acute onset exacerbations. altogether 54 infections were identified serologically, of which 23 (42.6%) were associated with exacerbations. this corresponded to 24.2% of the recorded exacerbations during the study period. the respiratory pathogens accounted fo ...19902298361
prospective study of the aetiology and outcome of pneumonia in the community.a prospective one-year study of community pneumonia was conducted in nottingham. 236 of 251 episodes of pneumonia (defined as an acute lower respiratory tract infection, for which antibiotics were prescribed, associated with new focal signs on examination of the chest) were investigated. acute radiographic changes were present in 93 (39%). a pathogen was identified in 129 (55%) episodes, with streptococcus pneumoniae, haemophilus influenzae, and influenza viruses those most frequently identified ...19872882091
whooping cough and unrecognised postperinatal mortality.trends in postperinatal infant mortality from respiratory causes and the sudden infant death syndrome in england and wales for 1968 to 1984 were examined. these were compared by time series analysis with changes in the incidence of specific infective diseases and organisms for the same period. discontinuity was found in association with the occurrence of whooping cough between 1977 and 1982. associations with the general incidence of respiratory infections and other specific organisms were less ...19883126714
the emmy klieneberger-nobel award lecture. appealing attributes of mycoplasmas in cell biology research. 19873312091
mycoplasma mastitis outbreak. 19863716113
a study on the virus aetiology of mild respiratory infections in the primary school child. 19674294573
pneumonia in childhood. 19684303487
family-based epidemiologic studies. the second wade hampton frost lecture. 19744360766
acute viral respiratory infections in a general practice during 1971. 19734375716
the effect of irradiation on intra-erythrocytic stages of babesia major. 19724621840
[serological and morphological (electron microscopic) study of mycoplasma isolated in bulgaria and abroad]. 19724663872
incidence of mycoplasma infection in guinea-pigs. 19714937498
antibody to mycoplasma hominis in patients with respiratory disease.an attempt was made to evaluate the role of mycoplasma hominis in respiratory infection in adults. sera collected from patients admitted to hospital with respiratory infections were examined for antibody to m. hominis. the incidence of antibody was no higher than that found previously in patients without respiratory disease.19705488037
feline infectious anaemia in the london area. 19705528577
pneumonia. present-day experiences and trends. 19685708154
a prospective study of chlamydial, mycoplasmal, and viral infections in a neonatal intensive care unit.in a prospective study of non-bacterial infection in a neonatal intensive care unit in north west london, chlamydia trachomatis infection was identified in 4 of 280 babies (1.4%) and was the most common cause of neonatal ophthalmia. one of the four developed pneumonitis. ureaplasma urealyticum was found to colonise the nasopharynx in 53 of 235 babies (22.6%), with mycoplasma hominis present in 6 of 235 babies (2.6%). there was a statistically significant association between u urealyticum colonis ...19846322705
adult community-acquired pneumonia in central london.strep. pneumoniae was diagnosed as the cause of pneumonia in 40 (50%) of 80 consecutive adults admitted to st stephen's hospital with community-acquired pneumonia. none of the patients had evidence of mycoplasma pneumoniae infection, and legionella pneumophila serology was positive on only one occasion. in 29 patients (36%) no causative organism was demonstrated. the diagnosis of pneumococcal infection was obtained in 15 cases by isolating strep. pneumoniae from the sputum, in 13 further cases b ...19846747977
derrick graham ff. edward: a pioneer in mycoplasmology. 19826750756
the 1888 pneumonia in middlesbrough. 19807017136
the effect of genital mycoplasmas on human fetal growth.the relation between maternal genital colonization by mycoplasmas and fetal growth was examined in a study of 195 women. swabs were taken from the endocervix on three occasions during pregnancy and once post partum. ureaplasma urealyticum organisms (ureaplasmas) were recovered from 42.7 per cent of caucasian women and from 34.6 per cent of asian women at their first antenatal visit. these isolation rates remained similar throughout pregnancy, although there was a decrease in isolation after deli ...19817248235
causes of pneumonia presenting to a district general hospital.the incidence of bacterial, viral, mycoplasma, and rickettsial infections has been assessed prospectively in 210 adult patients with pneumonia who presented to a district hospital over a six-year period. one hundred and thirteen infective agents were detected in 103 patients. the agent most frequently detected was mycoplasma pneumoniae which accounted for 30 infections. a bacterial pathogen was found in 43 patients. streptococcus pneumoniae was the most common of these (24 patients); staphylococ ...19817314031
the etiology of community-acquired pneumonia among hospitalized patients during a chlamydia pneumoniae epidemic in finland.the etiology of community-acquired pneumonia during a chlamydia pneumoniae epidemic was studied among 125 hospitalized patients. etiologic investigations included blood and sputum cultures, pneumococcal antigen detection, and serologic investigations for common respiratory viruses and for streptococcus pneumoniae, haemophilus influenzae, moraxella catarrhalis, mycoplasma pneumococcal antigen detection, and serologic investigations for common and for streptococcus pneumoniae, haemophilus influenz ...19957594672
a longitudinal study of bacterial vaginosis during pregnancy.to determine the longitudinal changes in the incidence of vaginosis in pregnancy.19947826957
prospective study of aetiology and outcome of adult lower-respiratory-tract infections in the community.community-acquired adult lower-respiratory-tract infections (lrti) are generally thought to be caused by atypical and viral infections. we have studied 480 adults presenting to a single general practice with community-acquired lrti between november, 1990, and december, 1991. the overall incidence was 44 cases per 1000 population per year; the incidence was 2-4 times higher in people aged 60 and over than in those aged less than 50. 206 patients were studied in detail; among this group 91 (44%) h ...19938094769
acute respiratory infections, and influenza vaccine for 1999/2000. 199910204284
the association of mycoplasma hominis, ureaplasma urealyticum and mycoplasma genitalium with bacterial vaginosis: observations on heterosexual women and their male partners.the prevalence of 3 mycoplasmas (mycoplasma hominis, ureaplasma urealyticum and mycoplasma genitalium) was determined in a cohort of women with or without bacterial vaginosis (bv) and in their respective male partners. heterosexual women with or without bv and their male partners were recruited and genital sampling for these microorganisms was performed. seventeen women with bv and 21 women with normal flora, and their respective male partners, were recruited. m. hominis was present in 9 (53%) o ...200010872907
rationalised prescribing for community acquired pneumonia: a closed loop audit.to audit the management of community acquired pneumonia before and after the introduction of a protocol. to determine the aetiology of pneumonia using routine investigations and polymerase chain reaction (pcr).200010999868
infectious agents associated with respiratory disease in pheasants.in a case-control study of the infectious agents associated with natural outbreaks of respiratory disease in pheasants, 28 batches of birds from sites affected by disease and eight batches of birds from unaffected sites were examined by six veterinary laboratories in england, wales and scotland, and tested for mycoplasmas, other bacteria and viruses. sinusitis was the commonest sign of disease and was associated with mycoplasma gallisepticum as detected by pcr in the trachea (p < 0.05) and conju ...200212054135
observations on eaton primary atypical pneumonia agent and analogous problems in animals. 196314064932
influenza a community-acquired pneumonia in east london infants and young children.community-acquired pneumonia (cap) is common in young children, but there are few data in europe on influenza a virus as a cause of childhood cap. the aim of this study was to determine the relative contributions of different etiologic agents to cap in children.200314551480
evaluation of an egg yolk enzyme-linked immunosorbent assay antibody test and its use to assess the prevalence of mycoplasma synoviae in uk laying hens.the frequency of mycoplasma synoviae exposure in a convenience sample of commercial layers was established by the presence of antibody in eggs. chloroform-extracted egg yolks were found to be more suitable than saline-extracted yolks, and were used with a commercial enzyme-linked immunosorbent assay kit, having first established the sensitivity and specificity of the kit with eggs from known m. synoviae-positive and m. synoviae-negative flocks. for the prevalence study, pooled yolks from 12 eggs ...200414681073
mycoplasma genitalium in chronic non-gonococcal urethritis.seventy-eight men with a history of chronic urethritis were referred for investigation. of 52 men diagnosed as having persistent or recurrent non-gonococcal urethritis (ngu) at the time of referral, 11 (21%) were infected with mycoplasma genitalium and three with chlamydia trachomatis. men who were m. genitalium-positive had not previously received less antibiotic, in terms of treatment duration, than those who were m. genitalium-negative, suggesting a possible resistance to the antibiotics give ...200414769166
mycoplasma bovis isolated from brain tissue of calves. 200515816191
isolation of mycoplasmas from pigeons suffering eye lesions and respiratory disease. 200516299371
detection of simkania negevensis by culture, pcr, and serology in respiratory tract infection in cornwall, uk.respiratory tract infections are often treated empirically without investigation to detect the aetiological agent, which may be a virus or a bacterium, including atypical pathogens such as chlamydophila pneumoniae or mycoplasma pneumoniae. recently, several types chlamydia-like intracellular bacteria have been detected in environmental samples and clinical specimens. little is known of their geographical distribution and potential pathogenicity. we describe the detection, by pcr and isolation in ...200616505289
mycoplasma genitalium is associated with symptomatic urethritis.in order to further investigate the epidemiology of mycoplasma genitalium, 680 men attending departments of genitourinary medicine in bristol, bath and truro were studied. m. genitalium was detected in 36 men (5.3%) and was present at all three clinics. clinically, both urethritis and the presence of a urethral discharge and/or dysuria, but not penile irritation were independently associated with the detection of m. genitalium, the former being with the strongest association (odds ratio [or] 10. ...200616643675
influenza, campylobacter and mycoplasma infections, and hospital admissions for guillain-barré syndrome, england.guillain-barré syndrome (gbs) is the most common cause of acute flaccid paralysis in polio-free regions. considerable evidence links campylobacter infection with gbs, but evidence that implicates other pathogens as triggers remains scarce. we conducted a time-series analysis to investigate short-term correlations between weekly laboratory-confirmed reports of putative triggering pathogens and weekly hospitalizations for gbs in england from 1993 through 2002. we found a positive association betwe ...200617326939
ten years of viral and non-bacterial serology in adults with cystic fibrosis.viral infections are associated with pulmonary exacerbations in children with cystic fibrosis (cf), but few studies have addressed the frequency in adults. this paper investigates the frequency and impact of viral infections in adults with cf receiving intravenous antibiotics. pre- and post-treatment spirometry, inflammatory markers and antibody titres against influenza a, influenza b, adenovirus, respiratory syncytial virus, mycoplasma pneumoniae, chlamydia psittaci, and coxiella burnetti were ...200817352838
mycoplasma mastitis. 200717369483
the prevalence of urethral and rectal mycoplasma genitalium and its associations in men who have sex with men attending a genitourinary medicine clinic.to determine the prevalence of rectal and urethral mycoplasma genitalium (mg) in men who have sex with men (msm) attending a genitourinary medicine clinic and to measure its associations with symptoms, clinical signs, sexual behaviour and concomitant sexually transmitted infections (sti).201019843536
the occurrence of mycoplasma phocicerebrale, mycoplasma phocidae, and mycoplasma phocirhinis in grey and common seals (halichoerus grypus and phoca vitulina) in the united kingdom.following the isolation of mycoplasma phocicerebrale from the flipper wound of a grey seal (halichoerus grypus) in cornwall, uk, surveillance for mycoplasma species was extended to include other seals rescued or found dead around the uk. mycoplasma phocicerebrale was frequently detected from the teeth of seals and from infected wounds and respiratory tracts. mycoplasma phocirhinis, mycoplasma phocidae, and some unidentified mycoplasma species were also detected. mycoplasma phocicerebrale and m. ...201121441202
increased incidence of mycoplasma pneumoniae infection in england and wales in 2010: multiocus variable number tandem repeat analysis typing and macrolide susceptibility. 201121596009
mastitis and arthritis in two dairy herds caused by mycoplasma bovis. 200717259455
herpesvirus outbreak in a group of mediterranean tortoises (testudo spp).chhv and mycoplasma agassizii infections in tortoises share similar clinical signs of lethargy, anorexia, rhinitis, and conjunctivitis. in addition, chhv infection is associated with glossitis and stomatitis and often causes high morbidity and mortality. as was seen in this case, chhv infection tends to cause higher mortality in t hermanni compared with t graeca and t marginata. t horsfieldi is also considered highly susceptible to chhv but appeared unaffected in this outbreak.200616931376
mycoplasma pneumoniae in elderly patients with stroke. a case-control study on the seroprevalence of m. pneumoniae in elderly patients with acute cerebrovascular disease - the m-peps study.previous studies have suggested certain infections as potential risk factors for stroke. chlamydia pneumoniae, an atypical respiratory pathogen, has been linked to atherosclerotic vascular diseases. mycoplasma pneumoniae, another atypical respiratory micro-organism, can rarely cause stroke. we investigated whether serological markers of m. pneumoniae infection were associated with acute stroke or transient ischaemic attack (tia) in elderly patients.200415026614
detection of mycoplasma ovipneumoniae in pasteurella-vaccinated sheep flocks with respiratory disease in england. 200314682543
an association of disseminated mycoplasma fermentans in hiv-1 positive patients with non-hodgkin's lymphoma.we examined the relationship between the haematogenous dissemination of mycoplasma fermentans and non-hodgkin's lymphoma (nhl) in 265 hiv-1 positive patients. a polymerase chain reaction (pcr) assay was used to detect m. fermentans in peripheral blood mononuclear cells (pbmcs) from 50 patients enrolled consecutively from an hiv outpatient clinic in 1991 (cohort 1), 56 patients with lower respiratory tract infection who underwent bronchoscopy in 1992 (cohort 2), and 159 patients who were enrolled ...200111487389
molecular detection of mycoplasma conjunctivae in english sheep affected by infectious keratoconjunctivitis. 200111289552
acute viral infections of upper respiratory tract in elderly people living in the community: comparative, prospective, population based study of disease burden.to evaluate the disease burden of upper respiratory infections in elderly people living at home.19979366736
is mycoplasma pneumonia associated with childhood acute lymphoblastic leukemia?acute lymphoblastic leukemia (all) in the childhood peak may be a rare response to delayed first exposure to one or more common infectious agent(s). mycoplasma pneumonia has the appropriate socioeconomic correlates and clinical symptoms and the hypothesis that delayed first exposure to it may contribute to all is considered. counts of positive reports of m pneumonia from disease surveillance data for england and wales (united kindom) for 1975-92 have been taken as proxies for community burden of ...19979328203
the organisms reported to cause infective myocarditis and pericarditis in england and wales.it is difficult to acquire an overall perspective of the range of organisms responsible for infective myocarditis or pericarditis, and their relative importance, as most studies have involved only case reports or case series of a single organism. this study analyses reports to the communicable disease surveillance centre, of the public health laboratory service. reports where myocarditis or pericarditis was included as the main clinical features between 1990 and 1993 were studied. between 1990 a ...19968793712
current respiratory infections. 19957532521
isolation of exotic mycoplasmas from sheep in england. 19836665959
studies on an epidemic of respiratory disease caused by mycoplasma pneumoniae. 19676017522
antibody to mycoplasma pneumoniae in normal subjects and in patients with chronic bronchitis. 19685250129
prevalence of pig herds affected by pleuropneumonia associated with haemophilus pleuropneumoniae in eastern england.a survey for the macroscopic lesions indicative of pneumonic infection in the pig with haemophilus pleuropneumoniae was made in an abattoir in eastern england. a total of 78 herds located in 11 counties of eastern or central england were seen between december 1982 and august 1983. lesions were noted in the batches submitted by 44 (56 per cent) of the 78 herds. a further 16 herds (21 per cent) submitted batches containing pigs affected by pleurisy principally of the caudal lobes but without the p ...19854049707
cot deaths in birmingham.the spatial and temporal distributions of cot deaths and of infant respiratory deaths in birmingham between 1964 and 1984 were examined. respiratory deaths declined and cot deaths increased, and the combined rate showed a downward trend. seasonal variations were identical in the two groups and in each case were more powerfully related to date of death than to date of birth. cumulative mortalities were parallel by age, depended crucially upon the quarter of the year in which the child was born, a ...19911958402
isolation of mycoplasma agalactiae var bovis from a calf pneumonia outbreak in the south of england. 19751154637
a general practice survey of the incidence of mycoplasma pneumoniae infections.an epidemiological survey was carried out at two centres in the north of england (liverpool and sunderland). one hundred and twenty patients were included in this survey to determine the relative incidence of mycoplasma pneumoniae infections in patients who present to their physician with an acute lower respiratory tract infection. data were available at the end of the survey in 115 patients. only one patient had a positive test for m.pneumoniae. there were nine patients who had a positive antib ...1976955701
epidemiology of mycoplasma pneumoniae infection in the united kingdom: an analysis of reports to the public health laboratory service of england and wales.infection with mycoplasma pneumoniae appears to follow a cyclic pattern in the united kindom, with periods of increased prevalence lasting about two years. outbreaks occurred in 1971-1972 and 1974-75, and probably also in 1967-68. infection confirmed by laboratory tests appeared to be commonest in older children, especially those aged 5-14, and least common in adults over 65 years of age. lower respiratory tract infection was the clinical feature most frequently reported.1976955698
isolation of mycoplasma canadense from an outbreak of bovine masitis in england. 1978685107
mycoplasma pneumoniae infections in children.details are given of all serologically confirmed mycoplasma pneumoniae infections in children referred to bristol hospitals during an epidemic lasting 18 months. 44 children, many below school age, had lower respiratory infections. the majority had cough and malaise which had failed to respond to antibiotics given before referral. chest x-rays showed no pathognomonic features: segmental or patchy consolidation was common; 3 cases of lobar consolidation. cold agglutinins were raised in 9 out of 1 ...1978626517
farm level risk factors associated with severity of post-weaning multi-systemic wasting syndrome.a cross-sectional study involving 147 pig farms across england was conducted in 2008-2009. farm severity of post-weaning multi-systemic wasting syndrome (pmws) was estimated through the use of an algorithm that combined data on post-weaning mortality, pmws morbidity and proportion of porcine circovirus type 2 pcr positive pigs. farms were classified as non/slightly, moderately or highly affected by pmws. data on potential pmws risk factors were collected through interviews, on-farm assessment an ...201121741715
prevalence of mycoplasma encephalitis. 201121616452
mycoplasma pneumoniae infection in primary care investigated by real-time pcr in england and wales.real-time pcr was employed to detect a conserved region of the p1 cytadhesin gene of mycoplasma pneumoniae in combined nose and throat swabs collected from patients attending gp surgeries during 2005-2009 with symptoms of respiratory tract infection (rti). samples were collected as part of an annual winter epidemiological and virological linked study in england and wales. a total of 3,987 samples were tested, 65 (1.7%, 95%ci 1.3-2.1) had detectable m. pneumoniae dna. positive patients were detec ...201121311941
the prevalence of three species of feline haemoplasmas in samples submitted to a diagnostics service as determined by three novel real-time duplex pcr assays.three distinct species of feline haemoplasmas are recognised: mycoplasma haemofelis (mhf), candidatus mycoplasma haemominutum (cmhm) and candidatus mycoplasma turicensis (cmt). these species differ in pathogenicity as mhf and cmt can be associated with anaemia whereas cmhm usually results in few clinical signs. the purpose of this study was to develop quantitative real-time pcr assays for the detection of all three feline haemoplasma species combined with an endogenous internal control and to de ...200817689890
Mycoplasma pneumoniae and respiratory virus infections in children with persistent cough in England: a retrospective analysis.Persistent cough following an acute respiratory tract infection is common in children, but clinicians may find it difficult to give accurate prognostic information on likely duration of cough without a microbiologic diagnosis. This study estimates the prevalence of Mycoplasma pneumoniae (Mp) and assesses the prognostic value of detecting Mp and respiratory viruses in children with persistent cough.201121857262
prevalence of mycoplasma genitalium in early pregnancy and relationship between its presence and pregnancy outcome.mycoplasma genitalium is associated with cervicitis and pelvic inflammatory disease but little is known about its role in pregnancy. we investigated the prevalence of m. genitalium by polymerase chain reaction assay on urine specimens from 1216 pregnant women (mean age 31years) presenting before 10 weeks of gestation in 32 general practices. the prevalence of m. genitalium was 0.7% (6/915, 95% ci 0.1-1.2). it was more common in women aged < 20 years, women of afro-caribbean or black african ethn ...200415663138
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