| acute infection with sin nombre hantavirus without pulmonary edema. | acute infection with sin nombre virus has been associated with development of hantavirus cardiopulmonary syndrome (hcps), a severe cardiopulmonary illness with respiratory failure and shock. we present two cases of sin nombre hantavirus infections that did not lead to marked pulmonary complications in two otherwise healthy young adults from utah and california. sin nombre virus causes a wider spectrum of disease severity than has been previously reported. | 1999 | 10530462 |
| changes in sin nombre virus antibody prevalence in deer mice across seasons: the interaction between habitat, sex, and infection in deer mice. | we examined the impact of season and habitat on sin nombre virus (snv) seroprevalence in deer mice (peromyscus maniculatus) in utah's great basin desert from may 2002 through summer 2003. low mouse captures in 2002 limited analysis for that year. in two seasons during 2003, mouse density and sagebrush cover were positively linked (spring: r = 0.8, p = 0.01; summer: r = 0.8, p = 0.04). in the spring, seroprevalence was negatively correlated with density (r = -0.9, p< 0.01); male and female antibo ... | 2006 | 17255449 |
| differential regulation of pathogens: the role of habitat disturbance in predicting prevalence of sin nombre virus. | deer mice (peromyscus maniculatus) are the primary reservoir for sin nombre virus (snv), a north american hantavirus that causes disease with high mortality in humans. recent studies have proposed that habitat disturbance affects prevalence of snv in deer mice; however, the outcomes proposed in these studies are in opposition to each other. our objectives were to test these divergent hypotheses by: (1) measuring snv infection in deer mice within a patchwork of disturbance; and (2) evaluating the ... | 2008 | 18064494 |
| seasonal variation in sin nombre virus infections in deer mice: preliminary results. | the proportion of deer mice (peromyscus maniculatus) with recently acquired sin nombre virus (snv) infections is an indicator of epizootic intensity and may be key in predicting outbreaks of hantavirus cardio-pulmonary syndrome in humans. we investigated whether incidence of recent infections was related to season, sex, reproductive status, or habitat disturbance. in may and september, 2006, we sampled 912 deer mice at six sites in utah. we determined snv antibody prevalence and estimated the nu ... | 2009 | 19395752 |
| testing mechanisms of the dilution effect: deer mice encounter rates, sin nombre virus prevalence and species diversity. | species diversity has been shown to decrease prevalence of disease in a variety of host-pathogen systems, in a phenomenon termed the dilution effect. several mechanisms have been proposed by which diversity may decrease prevalence, though few have been tested in natural host-pathogen systems. we investigated the mechanisms by which diversity influenced the prevalence of sin nombre virus (snv), a directly transmitted virus in deer mice (peromyscus maniculatus). we monitored both intra and intersp ... | 2009 | 19495881 |
| long-term patterns of immune investment by wild deer mice infected with sin nombre virus. | immunocompetence of animals fluctuates seasonally, however, there is little consensus on the cause of these fluctuations. some studies have suggested that these patterns are influenced by changes in reproductive condition, whereas others have suggested that differences result from seasonal variations in energy expenditures. the objective of our study was to examine these contrasting views of immunity by evaluating seasonal patterns of immune response and reproduction in wild populations of deer ... | 2010 | 20695811 |