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evaluation of a two-dose administration of live oral poliovirus vaccine for wild and virulent vaccine-derived poliovirus type 1, 2, 3 strains in japan.we evaluated the efficacy of japan's vaccination policy, a 2-dose administration of live oral poliovirus vaccine (opv) against wild and virulent vaccine-derived poliovirus (vdpv) type 1, 2, 3 strains, by investigating the neutralizing antibody titers of residents in toyama prefecture, japan. seropositivities against the virulent type 1 and 2 strains were more than 90%, but the values against the virulent type 3 strains were approximately 60%. also, while geometric mean antibody titers against vi ...200817907043
assessment of efficacy of a live oral poliovirus vaccine for virulent sabin-like poliovirus 1 strains in japan.virulent sabin-like poliovirus (vslp) was isolated from river and sewage waters between october 1993 and september 1995 in toyama prefecture, japan (yoshida et al., lancet 356, 1461-1463, 2000). in this study, to assess the possibility of an epidemic of poliomyelitis caused by a vslp in japan under the current vaccination policy of administration of live attenuated oral poliovirus vaccine (opv), we determined titers of serum neutralizing antibodies to poliovirus 1 (pv-1) strains sabin (vaccine s ...200616808333
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