| the biology and molecular biology of scrapie-like diseases. | the transmissible spongiform encephalopathies (tse's) are degenerative diseases of the central nervous system which naturally affect man (creutzfeldt-jakob disease [cjd], gerstmann-sträussler syndrome [gss], kuru), sheep and goats (scrapie), cattle (bovine spongiform encephalopathy [bse]), mink (transmissible mink encephalopathy), mule deer, elk and antelope (chronic wasting disease). spongiform encephalopathies have also been diagnosed in captive species of zoo antelope and in domestic cats. mu ... | 1993 | 8219804 |
| the relationship between new variant creutzfeldt-jakob disease and bovine spongiform encephalopathy. | creutzfeldt-jakob disease (cjd) has been transmitted in the laboratory and also by iatrogenic accident. however, research has failed to find evidence that its most common form (sporadic cjd) is a natural infection and, in particular, that there is a causal link with scrapie. bovine spongiform encephalopathy (bse) probably resulted from scrapie infection in cattle food. in the wake of the bse epidemic, a novel clinico-pathological form of cjd has been recognized: new variant cjd (nvcjd). this pap ... | 1999 | 10394138 |
| [functional risk assessment of handling of sheep housing and pasture areas at a scrapie-infested farm in mecklenburg-west pomerania]. | in the wake of a scrapie monitoring programme 2002 in mecklenburg-westpomerania a total of 10 positive cases were identified after culling at a suffolk-farm with about 1000 animals. scientific based recommendations are difficult to judge as longitudinal studies and subsequent quantitative risk factors regarding the epidemiology of scrapie are either not available or conflicting. given this background a risk assessment was developed that is based on the probability of validated risk factors consi ... | 2004 | 15188682 |
| atypical scrapie in sheep from a uk research flock which is free from classical scrapie. | in the wake of the epidemic of bovine spongiform encephalopathy the british government established a flock of sheep from which scrapie-free animals are supplied to laboratories for research. three breeds of sheep carrying a variety of different genotypes associated with scrapie susceptibility/resistance were imported in 1998 and 2001 from new zealand, a country regarded as free from scrapie. they are kept in a purpose-built sheep unit under strict disease security and are monitored clinically an ... | 2009 | 19208228 |