| prion protein gene polymorphisms in healthy and scrapie-affected spanish sheep. | the rasa aragonesa sheep is the second most important spanish breed after the merino breed. reported here is the prion protein (prp) haplotype frequency distribution for scrapie-related codons (136, 154 and 171) and a sequencing study of the complete prp gene open reading frame for this breed and six other closely related breeds. the study includes four scrapie-affected sheep flocks belonging to rasa aragonesa and rasa navarra breeds. thirty-eight scrapie-affected sheep, 502 healthy sheep from s ... | 2004 | 15218196 |