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retrospective review of dot enzyme immunoassay test for typhoid fever in an endemic area.typhoid fever remains a common problem in malaysia, but for its diagnosis both blood culture and the widal test have drawbacks. a dot enzyme immunoassay (eia) has been developed which detects igm and igg antibodies to a specific 50 kda outer membrane protein on salmonella typhi. this study was performed among outpatients attending the university hospital in kelantan, a state on the east coast of peninsular malaysia where typhoid is endemic. the dot eia was done on 149 outpatients of all ages in ...19959139364
antimicrobial susceptibility and distribution of non-typhoidal salmonella serovars isolated in malaysian children.there is widespread resistance of salmonella species to commonly prescribed antimicrobials the world over. we aimed to determine the antimicrobial susceptibility and serovar distribution of non-typhoidal salmonella (nts) isolated from blood cultures of malaysian children. positive isolates of nts from blood cultures obtained from children admitted to the pediatric wards of university of malaya medical center (ummc), a large urban hospital from kuala lumpur (1991-2001), and hospital kota bharu (h ...200312630719
rapid and reliable serological diagnosis of enteric fever: comparative sensitivity and specificity of typhidot and typhidot-m tests in febrile malaysian children.the typhidot test, which detects igm and igg antibodies to a salmonella typhi-specific outer membrane protein, is as sensitive as, and more specific than, the widal test in the diagnosis of enteric fever in malaysian children. it is easier and quicker to perform. in order to increase diagnostic accuracy in an area of high endemicity, the typhidot-m test has been developed in which igg is first removed. this theoretically allows improved detection of igm, and thus would differentiate new from rec ...199910206117
longevity of antibody responses to a salmonella typhi-specific outer membrane protein: interpretation of a dot enzyme immunosorbent assay in an area of high typhoid fever endemicity.the objective of this study was to investigate the longevity of positive dot enzyme immunosorbent assay (dot eia) results for igm and igg to a salmonella typhi outer membrane protein in malaysian children with enteric fever. the patients were children one month to 12 years of age with clinical evidence of typhoid fever, positive blood or stool cultures for s. typhi, and/or a positive widal test result who were admitted over a two-year period to general hospital (kota bharu, malaysia). these pati ...19979430522
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