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purification and variability in thrombin-like activity of bothrops atrox venom from different geographic regions.bothrops atrox snake venoms from two different amazon regions, i.e., manaus, am (3 degrees 0.6'40"s; 60 degrees 0.1'6.0"w) and tucurui, pa (3 degrees 0.42'30"s; 49 degrees 0.41'45"w), were analyzed with respect to the thrombin-like activity component by elution profile on gel-filtration and reverse phase hplc chromatography, electrophoretic mobility on sds-page, and enzymatic activity on fibrinogen. despite some individual discrepancies among venom specimens, the thrombin-like activity present i ...19989620574
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