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human t and b cell immunoreactivity to a recombinant 23-kda cryptosporidium parvum antigen.cryptosporidial infection in humans results in parasite-specific igg, igm, and iga antibody responses, but little is known of the cell-mediated immune responses to cryptosporidial antigens. in a convenience sample of 35 haitian residents, there was a high level of cryptosporidial exposure (>90%) as determined by immunoblot reactivity of serum against cryptosporidial antigens. an attempt was made to determine if there was a relationship between antibody and t cell-mediated responses to recombinan ...200111426740
cloning and characterization of the acidic ribosomal protein p2 of cryptosporidium parvum, a new 17-kilodalton antigen.cryptosporidium infection is commonly observed among children and immunocompromised individuals in developing countries, but large-scale outbreaks of disease among adults have not been reported. in contrast, outbreaks of cryptosporidiosis in the united states and canada are increasingly common among patients of all ages. thus, it seems likely that residents of regions where cryptosporidium is highly endemic acquire some level of immunity, while residents of the developed world do not. a new immu ...201020410328
[human cryptosporidiosis and cryptosporidium spp. in haiti].contamination by water-born infectious diseases is closely linked to urban slums conditions such as overcrowding and high level of faecal pollution by animal and human excreta. in this environment, cryptosporidiosis is a major cause of acute diarrhoea in children and chronic persistent diarrhoea in aids patients, resulting in increased morbidity and mortality in both populations. the aims of this study conducted in port-au-prince, haiti were to: (i) determine the frequency of cryptosporidium inf ...200616772015
cryptosporidiosis stimulates an inflammatory intestinal response in malnourished haitian children.the mechanisms by which cryptosporidium parvum cause persistent diarrhea and increased morbidity and mortality are poorly understood. three groups of haitian children <18 months old were studied: case patients, children with diarrhea not due to cryptosporidium, and healthy control subjects. compared with both control groups, children with acute cryptosporidiosis were more malnourished (including measures of stunting [p=.03] and general malnutrition [p=.01]), vitamin a deficient (p=.04), and less ...200212089667
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