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human metapneumovirus and exacerbations of chronic obstructive pulmonary disease.respiratory viruses are a common trigger for exacerbations of chronic obstructive pulmonary disease (copd). human metapneumovirus (hmpv) is a paramyxovirus associated with respiratory tract infections and wheezing. our aim was to determine whether hmpv was associated with exacerbations of copd.200616412516
a 1-year experience with human metapneumovirus in children aged <5 years.human metapneumovirus (hmpv) is a recently discovered respiratory pathogen. we tested respiratory specimens for the presence of hmpv by reverse-transcription polymerase chain reaction. these specimens were obtained over a 1-year period from children aged <5 years and had negative results by the direct fluorescent antibody test for respiratory syncytial virus, influenza a and b, parainfluenza viruses 1-3, and adenovirus. overall, 54 (8.1%) of 668 individuals tested positive for hmpv. during march ...200415073675
conservation of the respiratory syncytial virus sh gene.respiratory syncytial virus (rsv) encodes a short (64 or 65 amino acids) hydrophobic (sh) protein whose function in viral replication and pathogenesis is not understood. we carried out molecular epidemiological studies of the sh gene during the 1998-1999 seasonal epidemic in new haven, connecticut. strains circulating during the epidemic were related to viruses identified worldwide. the sh gene transcriptional control signals were conserved in 70 (98.6%) of 71 isolates that we sequenced. the ded ...200010979923
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