Publications

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a note on the properties of urine excreted by grazing cattle. 19765629
bruce and the african trypanosomes. 197720787
letter: national dried milk. 197546066
comparison of the specificity of human and bovine tuberculin ppd for testing cattle. 2. south-eastern england.a tuberculin testing trial was carried out in eight counties of south-eastern england to compare the specificity for bovine tuberculosis of weybridge human ppd with that of rotterdam bovine ppd. the matching of these two tuberculins for potency in naturally infected cattle had already been established, the bovine ppd being approximately one-and-a-half times more potent than the human ppd per unit of weight. in 1110 cattle in 25 herds with histories of long-standing freedom from tuberculosis and ...197547751
comparison of the specificity of human and bovine tuberculin ppf for testing cattle. 3. national trial in great britain.a field trial on a country-wide basis was undertaken to compare the specificity for bovine tuberculosis of single and comparative tuberculin tests in cattle using either weybridge human or weybridge bovine ppd. the tests were made on 10,305 cattle in 179 herds distributed throughout all regions of england, scotland and wales. results showed that a comparative tuberculin test using avian ppd with either human or bovine ppd had a much higher efficiency than a single injection of mammalian tubercul ...197547752
editorial: bovine tuberculosis and badgers. 197550520
cot deaths and water-sodium.over a thirty-year period in scunthorpe, during which there were two changes in the sodium content of the water supply, there were significantly more sudden deaths in infancy during the decade when sodium levels were highest. this is compatible with the hypothesis that hypernatraemia is a factor leading to cot death. changes in the incidence of breastfeeding over the same period may have contributed to, but are unlikely to account for, the result because the pattern was different in a neighbouri ...197882031
decline in hypernatraemia. 197991864
congenital heart disease in liverpool: 1960--69.the incidence of congenital heart disease (c.h.d.) in liverpool from 1960 to 1969 inclusive has been determined from the liverpool congenital abnormalities registry with a follow-up period of 3 to 12 years. the incidence is 6-6 per 1000 total births and this probably represents a very small degree of under-reporting. there is no consistent seasonal variation in the incidence of any of the main congenital heart lesions. in general, infants with c.h.d. tend to be of lower birth weight and born aft ...1975125433
foot-and-mouth disease in british deer: transmission of virus to cattle, sheep and deer.after exposure for two hours to cattle with foot-and-mouth disease, each of the five species of deer found in the british countryside became infected. clinical disease was typical and severe in the roe and muntjac deer, with some animals dying, less severe in the sika deer and usually subclinical in the fallow and red deer. each species transmitted disease to its own species and to cattle and sheep. the amounts of virus present in the blood, and in oesophageal/pharyngeal samples and excreted as ...1975167503
infection of british deer and farm animals with epizootic haemorrhagic disease of deer virus. 1977198436
serological studies of mucosal disease virus in england and wales.a survey of the cattle population in england and wales showed that about 62 per cent of animals had neutralising (sn) antibody to bvd-md virus in their serum. fewer seropositive individuals were detected by immunodiffusion (53 per cent), and complement fixation (cf) tests (34 per cent). the prevalence of antibody was not affected by herd size, but some variation was found between various regions of the country, and the proportion of animals seropositive rose markedly with age. the immunodiffusio ...1978203990
a serological survey on the prevalence of infectious bovine rhinotracheitis in buckinghamshire, berkshire and oxfordshire.of the 2368 cattle sera from herds in buckinghamshire, berkshire and oxfordshire examined for infectious bovine rhinotracheitis antibody by an indirect haemagglutination test, 162 (6.8 per cent) proved positive. positive titres were more prevalent in older cows and they tended to show higher titres. there was little evidence of infection in the bulls tested. the percentage of positive animals in berkshire and oxfordshire was 4.7 compared with 10.5 in buckinghamshire. the infection was not known ...1978211700
virus-induced papillomas of the alimentary tract of cattle.an abattoir survey was carried out to determine the incidence and aetiology of squamous papillomas of the alimentary tract of cattle in scotland and north england as they were suspected of being involved in the genesis of alimentary carcinoma in certain localized geographical areas. a total of 7,746 cattle of a wide age range was examined. various subsets of this number were subjected to analyses of certain specific factors. the calculated overall incidence was 19% and the detailed site incidenc ...1978212374
the distribution of antibodies to border disease virus among sheep in england and wales.within a sample of the sheep population of england and wales, 10.8 per cent of 3506 individuals had immunodiffusion test antibody to bovine viral diarrhoea mucosal disease virus antigen. there were marked differences between various geographical regions in the proportion of sheep with antibody, and border disease may be more common in some areas than disease records indicate.1978214835
studies on bovine leukosis as it is seen in england and wales.a random series of 14 clinical cases of bovine leukosis as it is seen in england and wales has been studied clinically, haematologically, serologically (by the indirect fluorescent antibody test and later by agar gel immunodiffusion as well), virologically (for evidence of bovine leukaemia virus--blv) and using the electron microsocope to count intranuclear pockets in circulating lymphocytes. additionally calves have been inoculated with whole blood and a tissue lymphocyte suspension from the fi ...1978224793
incidence of salmonella infection in animals in england and wales 1968--1974.of a total of 23,609 incidents of salmonella infection reported during the period 1968--74, 20,326 occurred in cattle, 1744 in poultry and other birds, 675 in sheep, 558 in pigs and 306 in other species of animals. despite the large number of serotypes isolated (153), 88% of incidents were due to only two stereotypes: s. dublin (15,929 incidents of which 15,446 occurred in cattle ) and s. typhimurium (4842 incidents of which 3785 occurred in cattle and 732 in birds). s. choleraesuis was the thir ...1977319168
the rebound phenomenon of gordon holmes.contrary to a prevalent belief, the rebound phenomenon of gordon holmes is not a sign of cerebellar disease. it is elicited by having the patient attempt to move a limb against resistance. when the resistance is suddenly removed, the limb normally moves a short distance in the desired direction and then rebounds (jerks back in the opposite direction). gordon holmes pointed out that the rebound phenomenon is (1) present in normal libs, (2) exaggreated in spastic limbs, and (3) absent in limbs aff ...1977320970
evaluation of mastitis control programs. 1977326740
the serological relationship of a british theileria with other theileria species using the indirect fluorescent antibody test.antisera and antigens of a theileria species isolated from british cattle were compared with those of six strains of theileria mutans from geographically separated areas in east and south africa, using the indirect fluorescent antibody (ifa) test. it was found that the british theileria species did not react in the ifa test with these strains of t mutans. the british theileria species was also compared with a variety of other theileria species using the ifa test and no reactions were detected. i ...1977327522
salmonellas in milk. 1977337065
bloodless castrators. 1977337637
the farmers request by john bradstreet. 1978369104
clostridium botulinum in soil on the site of the former metropolitan (caledonian) cattle market, london.sixty soil samples were collected from the redeveloped site of the former metropolitan (caledonian) cattle market, islington, london. of these, 15 (25%) contained clostridium botulinum and no less than four types (b, c, d and e) were demonstrated. early british soil surveys suggested that only 4--8% of samples contained cl. botulinum (type a or b). although there can be no absolute proof, it seems likely that the striking prevalence at the market site was the result of faecal contamination by a ...1979385765
international spread of multiresistent strains of salmonella typhimurium phage types 204 and 193 from britain to europe. 1979390851
evolution of ideas on the life-span of the red blood cell. 1979399642
clinical disease in cattle in england resembling dalmeny disease associated with suspected sarcocystis infection. 1978413846
the prevalence of sarcocystis spp in dogs and red foxes.protozoan parasites of the genus sarcocystis have been recognised for many years as intramuscular cysts of numerous vertebrates. it is only comparatively recently that the two-host nature of the life cycle has been recognised and that the intramuscular cysts are a stage in the developmental cycle of coccidian parasites of flesh eating mammals (fayer 1974, fayer and johnson 1973, 1974, rommel and others 1972, dubey 1976). carnivores ingest the intramuscular cysts from herbivores and presumably fr ...1978416553
campylobacter enteritis associated with consumption of unpasteurised milk.in october and november 1978 two outbreaks of enteritis occurred in the north of england. symptoms lasted two to over eight days but in no case necessitated admission to hospital. faecal specimens from most of the patients were found to contain thermophilic campylobacter sp. inquiry disclosed that all patients had consumed unpasteurised milk from local farms. examination of rectal swabs from the cattle concerned and milk socks yielded strains of campylobacter sp indistinguishable from those isol ...1979444995
heberden oration 1978. recent studies on the control of joint damage: the contribution of the strangeways research laboratory. 1979485574
cattle association discusses preventive medicine. 1979505905
some epidemiological aspects of salmonellosis in relation to animal and human health. 1979511494
antibody studies in natural bovine cowpox.serological studies on cows recovered from natural cowpox indicated that haemagglutinin-inhibiting (hai) antibody persisted for at least 27 weeks, and virus neutralizing (vn) antibody persisted for at least 98 weeks.1979512354
anthrax in england and wales. 1979514969
mastitis--the perpetual problem. 1979516319
selenium status of cattle in devon. 1979516359
the effect of a preparturient fenbendazole treatment on lactation yield in dairy cows.studies carried out on nine farms in north-west england indicated that fenbendazole treatment of adult winter calving dairy cows in the dry period caused an overall increase of 173 kg in their subsequent lactation yield. there was some evidence to suggest that a correlation existed between pasture ostertagia ostertagi larval burdens and subsequent serum pepsinogen and milk yield responses post treatment. marked interherd and regional differences existed in the milk yield response to anthelmintic ...1979524709
infectious bovine rhinotracheitis. 1979552711
a survey of thelazia worms in the eyelids of british cattle.thelazia skrjabini and t gulosa were found in the eyes of 237 of 566 bovine heads (41.9 per cent) examined in a surrey abattoir during 1976. the prevalence of infection increased during late june, july and august, when a new generation of worms emerged in eyes. the burden in eyes ranged from one to 170 worms, with a mean count of 10.44 +/- 3.23. worms were found behind and in third eyelids and in the lacrimal ducts of lower eyelids, which makes their detection very difficult by clinical examinat ...1978565553
dietary fibre and regional large-bowel cancer mortality in britain.the relationship between food intake and cancer of the large bowel was assessed by calculating the average intakes of foods, nutrients and dietary fibre in the different regions of great britain and relating these to the regional pattern of death from colon and rectal cancers between 1969 and 1973. no significant associations were found with the consumption of fat, animal protein or beer, nor with current estimates of total dietary fibre intake. average intakes of the pentose fraction of total d ...1979574389
the influence of availability of free school milk on the height of children in england and scotland.the effect is investigated of availability of free school milk on height gain in one year of six- and seven-year-old primary schoolchildren in england and scotland, using data collected annually from 1972 to 1976. the height gain of children for whom milk was available for the whole year of observation was compared with that of children who had no milk. out of 16 sex-country-year-specific analyses for children from manual social classes only, 13 showed no significant evidence of greater height g ...1979574407
the control of cattle fertility; the use of computerized records. 1977608075
pregnancy toxaemia of beef cows in orkney.pregnancy toxaemia in beef cows is assessed based on approximately 30 isolated cases seen in orkney during the period 1974 to 1977. case histories of nine of these are included. a mortality rate of over 90 per cent was recorded. the importance of nutrition and early detection is emphasised.1978664198
isolation of mycoplasma canadense from an outbreak of bovine masitis in england. 1978685107
a critical analysis of condemnation data for cattle, pigs and sheep 1969 to 1975. 1978698775
observations on parasitic gastroenteritis and bronchitis in grazing calves: untreated calves. 1978751988
the distribution of serotypes of escherichia coli in cow-pats and other animal material compared with serotypes of e. coli isolated from human sources.the serotypes of 13,139 strains of escherichia coli isolated from humans were compared with the serotypes of 1076 strains isolated from animals. 689 of these strains were isolated from fresh cow-pats on 22 sites in england and wales. 708 different o/h combinations were found. of these, 520 were found in human strains only, 130 from animal strains only and 58 o/h serotypes from humans and animals. approximately half of the animal strains could not be typed with the full set of sera used.1976778259
the distribution of o-antigen types of escherichia coli in normal calves, compared with man, and their r plasmid carriage. 1976780334
cattle plague in coventry in the mid-eighteenth century. 1976788322
farewell to queen's hospital, sidcup. 1976793663
nutrition classics. nature 144:442-3; 1939; d. keilin and t. mann: carbonic anhydrase. 1976821024
[health measures in obtaining milk (a review of the foreign literature]. 1977847889
is cowpox misnamed? a review of 10 human cases.twelve separate outbreaks of confirmed cowpox, 10 involving humans, were reviewed. six of the patients, including three children, had severe infections and five were admitted to hospital. in three outbreaks both people and cows were affected but it was not known how the infections entered the herds. in seven outbreaks no direct contact with cattle was established and clinical and serological examination failed to show evidence of cowpox in the bovine population. comparison of these data with inf ...1977861644
salmonellae in waterways in north yorkshire associated with human and animal effluent. 1977882632
[phenylmercuric acetate poisoning in veal calves (author's transl)]. 1977882971
bovine babesianis: a case reported in devon, england. 1977884647
veterinary surgeons and the medicines (labelling) amendment regulations 1977.further changes to the medicine labelling regulations have important implications for practising veterinary surgeons. they amend the regulations made recently by specifying warning labels and other special labelling requirements for certain types of veterinary medical products.1977906227
isotopic composition of cattle pancreatic stones: biological and geochemical implications.latitudinal variations of the o18/o16-ratios of carbonate and phosphate of cattle pancreatic stones parallel a similar pattern of oxygen isotope values in rain water. c13/c12-ratios were virtually identical for the 7 cases studied. isotopic measurements of mammalian hard tissues may be used for studying short-term climatic variations through quaternary.1977923694
domestic animal transport regulations. 1977928643
the incidence of freemartins in heifer calves purchased from markets. 1976936453
brucellosis eradication in great britain. 1976941015
the establishment and operation of a central laboratory for pregnancy testing in cows. 1976963523
early diagnosis of non-pregnancy in cattle: the first eighteen months of a commercial service. 1976963524
composition of ewe's milk. 1976986407
some observations on "paralytic myoglobinuria" of cattle in britain. 1976997177
separation and recombination of babesia divergens and ehrlichia phagocytophila from a field case of redwater from eire.a blood sample received from a field case of redwater in eire caused simultaneous infections of babesia divergens and ehrlichia phagocytophila when inoculated into a splenectomised calf. each disease agent was isolated in a separate splenectomised calf by suppressive drug treatment of the other agent, and blood stabilates were made. the disease agents were inoculated synchronously or asychronously into groups of calves, whose reactions were observed. infection with b divergens had no effect on t ...19761006962
examination of slurry from cattle for pathogenic bacteria.one hundred and eighty-seven samples of slurry from cattle were examined forthe presence of salmonellas, pathogenic leptospires and brucellas. small numbers of salmonellas, generally less than 1/g., were isolated from 20 samples (11%). these were s. dublin (12), s. typhimurium (4), s. indiana (1), s. bredeney (1), s. cerro (1) and s. unnamed 4, 12:d:-(1). leptospires were isolated from 56 samples (30%) but none was pathogenic for hamsters. no brucellas were isolated. the results of this survey a ...19751054059
the effect of storage in slurry on the virulence of salmonella dublin.the mouse was used as a model to determine whether storage of salmonella dublin in slurry and in broth reduces the virulence of the organism. no reduction in virulence of s. dublin stored in slurry for 36 days or in maintenance broth for 70 days was observed. the disease hazard involved in pasture-spreading of slurry contaminated with salmonellas is related to factors other than virulence.19751054060
outbreaks of bovine salmonellosis caused by serotypes other than s. dublin and s. typhimurium.outbreaks of salmonellosis caused by serotypes other than s. dublin and s. typhimurium were investigated on 41 farms in north-west england. of these, 37 (90 per cent) were in dairy cows. there was strong circumstantial evidence that contaminated dairy cake was the source of infection in at least four herds and probably many more. twenty-six serotypes were encountered with s. newport, the commonest, causing the most severe disease. most cattle seemed to rid themselves of infection during the foll ...19751054726
trends in salmonella food poisoning in england and wales 1941-72.cattle and pig herds and flocks of domestic fowl have formed the main reservoir of human salmonella food poisoning in england and wales from 1941 to 1972. changes in the incidence of human salmonella food poisoning and in the serotypes of salmonellas isolated from human infections are shown to have been associated with the introduction of new foods, with changes in animal husbandry, and with changes in the relative proportions of flesh food from different species consumed. new foods, dried powde ...19751054731
salmonellosis in wild mammals.one thousand two hundred and sixty-nine freeliving, wild mammals, representative of 16 species from estates in berkshire, oxfordshire and surrey, were examined for the presence of salmonellas. salmonella typhimurium was isolated from 1 and s. dublin from 7 house mice (mus musculus). there were no isolations from the other species examined. it was concluded that the house-mice infected with s. dublin acquired the organism from experimentally infected cattle. the wild mammal population does not at ...19761068191
studies on the 1967--68 foot and mouth disease epidemic: incubation period and herd serial interval.the incubation period during this epidemic was studied using both a spectral analysis-cum-filtering method and analysis of case histories. using spectral analysis, the modal herd serial interval was estimated to be 8--10 days based on the record of the daily number of outbreaks and an adjusted cattler series. the case histories tended to confirm these estimates but indicated that the serial interval varied considerably between species. the filtering method revealed that the herd serial interval ...19761068194
epidemiological studies on the 1967-1968 foot-and-mouth disease epidemic: the reporting of suspected disease.from an analysis of the telephone reports in ten fmd control centres in the west midlands, the veterinary officers' reports on each outbreak, the farm patrol reports and the daily number of outbreaks announced on the 17.50 h b.b.c. t.v. news, it would appear that the reporting of suspected outbreaks was indirectly related to the local disease activity. private veterinary practitioners reported older cases of fmd at the beginning and end of the epidemic than in the middle.19761069810
letter: new forest disease. 19751114654
letter: brucellosis: nfu and the maff. 19751119080
letter: right-sided "splash". 19751119098
isolation of mycoplasma agalactiae var bovis from a calf pneumonia outbreak in the south of england. 19751154637
letter: drought in the west. 19751154638
anthrax in england and wales 1963-1972.the records of confirmed anthrax diagnoses held by the bacteriology department of the central veterinary laboratory, weybridge, for the years 1963 to 1972 inclusive, were analysed. during this decade, 86 per cent of the 2944 deaths recorded were in cattle and 11 per cent in pigs, correlating significantly with the cattle and pig populations in england and wales during this period. also, the country could be separated into high and low prevalence counties for cattle anthrax. norfolk and somerset ...19751179615
a large scale mastitis control programme in somerset.the results of a mastitis control programme operated in south west england for three years are given. farmers participating in the full mastitis control group agreed to treat each cow at drying off with 500 mg benzathine cloxacillin in each quarter, to have their milking machines tested and to correct any faults, and to practise teat dipping. data covering cell counts, milk production, milk quality and clinical mastitis, were assessed from herds taking part in the programme. cell counts were ana ...19751189238
letter: an anthrax outbreak. 19751198877
radioiodine(131i) in animal thyroids during nuclear tests in both hemispheres. 19751201953
liver fluke in great britain: a survey of affected livers.over a period of 15 months data were collected from abattoirs in great britain on 213,082 cattle and 362,838 sheep livers to determine the distribution and prevalence of damage by fasciola hepatica. the stock came from 8239 farms, and from livestock markets in 81 counties. 53 per cent of the farms had sent affected stock, with significant percentages in eastern as well as the western counties of england and scotland. 21 per cent of all cattle and 7 per cent of all sheep livers examined were affe ...19751202744
the economic aspect of spastic paresis of the hind legs of friesian cattle. 19751216428
a survey of drug resistance in salmonella isolated from animals in england and wales during 1972. 19761260419
the cost of summer mastitis.the incidence of summer mastitis on 95 dairy farms in southern england was monitored in the summer of 1987. data on the type of animal infected, the fate of the animals immediately and over the succeeding lactation, and the procedures used in treating the infections were collected for 144 cases. twenty-five per cent of cases were attended by veterinary surgeons. most of the animals received parenteral antibiotics and on average each received five tubes of intramammary antibiotic. the incidence o ...19921441135
update on the incidence of summer mastitis in england and wales. 19921462493
some aspects of the epidemiology and control of salmonella typhimurium infection in outwintered suckler cows.two outbreaks of salmonella typhimurium infections affected outwintered, spring-calving suckler cows in late pregnancy. the infections spread rapidly both within and between groups of stock on the affected farms, with morbidity in the infected groups varying from 14.5 per cent to over 60 per cent, and mortality in adult cattle varying from 0 to 14.3 per cent. prophylactic measures included the use of antibiotics and killed vaccines against escherichia coli, salmonella dublin, s typhimurium, and ...19921475896
outbreak of lameness in cattle. 19921496762
mycobacterium bovis in england and wales: past, present and future.this report reviews the literature concerning tuberculosis resulting from infection with mycobacterium bovis in man and cattle and summarises data derived from surveillance of m. bovis in england and wales from 1986 to 1990. of the 228 isolates of m. bovis examined in this period, 122 (53%) were from patients aged over 60 years and are largely the result of reactivation of infection acquired prior to the institution of control measures. however, eight isolates (3.5%) were from patients aged less ...19921499671
bovine spongiform encephalopathy: aspects of the clinical picture and analyses of possible changes 1986-1990.a standard questionnaire was used to record the presence of specific clinical signs reported for histopathologically confirmed cases of bovine spongiform encephalopathy observed before june 30, 1990, and the frequencies of these signs were analysed. the signs most frequently recorded were apprehension, hyperaesthesia and ataxia, and there were variations in the frequency with which some signs were recorded in animals observed at different times during the epidemic. these variations were consider ...19921509649
drug withdrawal periods. 19921509654
interpretation of bse statistics. 19921523798
bovine spongiform encephalopathy: epidemiological features 1985 to 1990.following the identification of bovine spongiform encephalopathy (bse) in the british cattle population in 1986 epidemiological studies were launched. this paper provides an updated account of the epidemiological features of bse from 1985, when the first cases, based on clinical histories, occurred, until 1990. the number of cases up to december 1989 represents an annual incidence of 3.9 confirmed cases per 1000 adult animals in great britain. many more dairy herds were affected than beef suckle ...19921557877
serology and anthrax in humans, livestock and etosha national park wildlife.results are presented from a number of epidemiological studies using enzyme immunoassays (eia) based on the purified anthrax toxin antigens, protective antigen, lethal factor and oedema factor. studies on sera from a group of 62 human anthrax patients in turkey and from cattle in britain following two unrelated outbreaks of anthrax show that eia using protective antigen can be a useful diagnostic aid and will detect subclinical infections in appropriate circumstances. a serological survey on wil ...19921582472
scrapie-like encephalopathy in a greater kudu (tragelaphus strepsiceros) which had not been fed ruminant-derived protein.a 19-month-old greater kudu (tragelaphus strepsiceros), whose dam had died 15 months earlier with spongiform encephalopathy, required euthanasia after developing severe ataxia and depression with an apparently sudden onset. no macroscopic abnormalities were detected on post mortem examination but a scrapie-like spongiform encephalomyelopathy was apparent on histopathological examination of brain and segments of spinal cord. negative stain electron microscopy of proteinase k-treated detergent ext ...19921604783
[spongiform encephalopathies with special reference to bovine spongiform encephalopathy].in switzerland bovine spongiform encephalopathy (bse) was detected for the first time in november 1990. it is a transmissible disease of the central nervous system similar to creutzfeldt-jakob disease (cjd), gerstmann-sträussler-scheinker syndrome (gss) and kuru in man, and, in animals, scrapie in sheep and goats, chronic wasting disease (cwd) in captive mule deer and elk of north america and transmissible mink encephalopathy (tme) of farm reared mink. the infectious agent of the spongiform ence ...19921615298
perinatal calf mortality. 19911659759
dual infection from cooked meats? 19911669791
epidemiological surveillance of creutzfeldt-jakob disease in the united kingdom.systematic epidemiological surveillance of creutzfeldt-jakob disease was carried out in england and wales covering the years 1970-1984. the results of this work provide a basis from which to assess any change in the pattern of creutzfeldt-jakob disease following the occurrence of bovine spongiform encephalopathy. the methodology, early results and problems of the current systematic national survey of cjd, initiated in may 1990, are discussed.19911761103
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