Publications

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a comparative study on polychlorinated biphenyls (pcb) and polychlorinated quaterphenyls (pcq) concentrations in subcutaneous fat tissue, blood and hair of patients with yusho and normal control in nagasaki prefecture.the relationship between pcb and pcq concentrations in the blood, subcutaneous fat tissue and hair was investigated in this study. pcb and pcq concentrations in twenty four patients with pcb poisoning (yusho) and 59 normal controls were analyzed. the alkaline decomposition method described in the official standard analytical methods for the isolation of pcb and pcq fractions was used. the mean value of pcb concentrations was 2.43 ppb, cb% ratio was 0.69 and the pcq concentration in the blood of ...19892501198
[introduction of the information processing system of medical examinations of yusho patients and some results obtained by the 1986 survey].information processing system for newly established, unified medical examinations of yusho patients which started in september 1985 was presented. some comparative analysis was also shown on the "important findings" in yusho patients residing in fukuoka or nagasaki prefecture. in the 1986 survey, fukuoka male patients showed higher percentages of pigmentation in toe nail, gingiva and palpebral conjunctiva than nagasaki (p less than 0.01), whereas nagasaki male patients showed higher percentages ...19892501202
a cohort study on mortality of "yusho" patients: a preliminary report.in 1968, a mass food poisoning (yusho) occurred in western japan involving more than 1,850 people, the majority of whom were residents of fukuoka and nagasaki prefectures. the poisoning is now understood to have been caused by ingestion of a commercial brand of rice oil contaminated with polychlorinated derivatives of biphenyls, dibenzofurans, quaterphenyls, and some other related compounds. the number of deaths seen among 1,761 victims (887 males and 874 females) from the date of official regis ...19873147283
[a longitudinal analysis on the association of serum lipids and lipoproteins concentrations with blood polychlorinated biphenyls level in chronic "yusho" patients].we examined the association between blood pcb level and the serum concentrations of total cholesterol, high-density lipoprotein cholesterol and triglycerides. the data was retrieved from the dataset of the nationwide health examination for yusho patients. we longitudinally analyze the laboratory data of the officially identified yusho patients who underwent the health examination in fukuoka and nagasaki prefectures five times or more during the years from 1986 to 2000. for the longitudinal analy ...200312872711
a comparative study on the concentrations of polychlorinated biphenyls (pcbs) and polychlorinated quaterphenyls (pcqs) in the blood and hair of "yusho" patients and inhabitants of nagasaki prefecture.the relationship between polychlorinated biphenyl (pcb) and polychlorinated quaterphenyl (pcq) concentrations in the blood and hair was investigated. the materials in this study consisted of 49 blood samples and hair obtained from 27 patients with pcb poisoning (yusho) and 22 normal controls. the alkaline decomposition method described in the official standard analytical methods for the isolation of pcb and pcq fractions was used. in the blood of the control group, the mean concentration of pcbs ...19911916602
increased levels of urinary nitrite and nitrotyrosine in yusho victims 40 years after accidental poisoning with polychlorinated biphenyls in nagasaki, japan.forty years have passed since the accidental poisoning with polychlorinated biphenyls (pcb) in japan in 1968, named yusho. high concentrations of pcb are still detected in the serum of the yusho victims. pcb produces superoxide (o(2) (-)) in the metabolic process and we reported high concentrations of serum nitrite, a stable metabolite reflecting nitric oxide (no), in the yusho victims. no reacts with o(2) (-) and immediately produces peroxynitrite (onoo(-)). onoo(-) causes nitration of tyrosine ...200818626891
sex ratio in offspring of those affected by dioxin and dioxin-like compounds: the yusho, seveso, and yucheng incidents.sex ratios in the offspring of those affected by dioxins or dioxin-like compounds have been reported from seveso, italy and yucheng, taiwan. the sex ratio of live births in yusho, japan after a similar accidental massive exposure to polychlorinated biphenyls (pcbs) and polychlorinated dibenzofurans (pcdfs) in 1968 are reviewed. data on all births among parents exposed to the compounds from 1968 to 1977 in fukuoka and a region of nagasaki, the two areas affected, are reported. in total there were ...200111452050
fetal pcb syndrome: clinical features, intrauterine growth retardation and possible alteration in calcium metabolism.pregnant mothers with yusho in fukuoka, nagasaki and kochi prefectures delivered babies with a peculiar clinical manifestation which will be called fetal pcb syndrome (fps). the birth rate incidences were 3.6% (fukuoka prefecture), 4% (nagasaki prefecture), 2.9% (kochi prefecture) and 3.9% (total). the manifestations consisted of dark brown pigmentation of the skin and the mucous membrane, gingival hyperplasia, exophthalmic edematous eye, dentition at birth, abnormal calcification of the skull a ...19853921362
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