Publications

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infectivity of the santa lucia (el salvador) strain of plasmodium falciparum to different anophelines.anopheles freeborni mosquitoes were much more heavily infected with the santa lucia strain of plasmodium falciparum from coastal el salvador than were any of the other species tested. of 5 strains of a. albimanus examined, the most heavily infected was the ca-109a and the least was the melara, both of which come from coastal el salvador. of the exotic anophelines, the a. maculatus was infected at a slightly higher level than was the a. balabacensis. the incidence of highly infected individual mo ...1977403273
studies on the santa lucia (el salvador) strain of plasmodium falciparum in aotus trivirgatus monkeys.the santa lucia strain of plasmodium falciparum was isolated from el salvador, central america, and established in aotus trivirgatus monkeys. transmission from monkey to monkey via the bites of infected anopheles freeborni, a. maculatus, and a, albimanus mosquitoes was obtained in 20 of 27 attempts. prepatent periods in the monkeys ranged from 17 to 46 days with a mean of 24.3 days. parasitemias and mortality were higher following sporozoite inoculation into animals which had been previously inf ...1977403272
salvador ii strain of plasmodium vivax in aotus monkeys and mosquitoes for transmission-blocking vaccine trials.infections with the salvador ii strain of plasmodium vivax in aotus lemurinus griseimambra monkeys were fed upon by anopheles freeborni mosquitoes. periods of mosquito infectivity were determined to establish a model system for the testing of transmission-blocking vaccines. the highest levels of mosquito infection were associated with the ascending asexual parasitemia after reaching 1,000/microl, and before the peak asexual parasite count. sporozoite-induced infections were more infectious than ...19989684622
the santa lucia strain of plasmodium falciparum as a model for vaccine studies. i. development in aotus lemurinus griseimembra monkeys.the santa lucia strain of plasmodium falciparum and the aotus lemurinus griseimembra monkey are proposed as models for the testing of sporozoite vaccines and transmission-blocking vaccines. approximately 85% of splenectomized monkeys were infected when fed upon by 10 or more heavily infected anopheles freeborni mosquitoes. sporozoite-induced infections in monkeys with or without previous infection with p. vivax readily infected mosquitoes, thus making them candidates for testing transmission-blo ...19968615450
further studies on the sporozoite transmission of the salvador i strain of plasmodium vivax.different species of saimiri and aotus monkeys were inoculated with sporozoites of the salvador i strain of plasmodium vivax. of 58 saimiri inoculated, 45 developed parasitemia (4 following bites and 41 following intravenous inoculation). prepatent periods ranged from 10 to 63 days. twelve of 19 monkeys inoculated with sporozoites that had been stored frozen developed patent parasitemia after 16-53 days. of 41 aotus monkeys inoculated, only 10 (2 via bites and 8 via intravenous inoculation) deve ...19948064516
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