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spongiform encephalopathy of rocky mountain elk.a disease with striking clinical and pathologic similarities to the spongiform encephalopathies is described in six rocky mountain elk (cervus elaphus nelsoni) maintained in wildlife facilities in colorado and wyoming. clinical signs included behavioral alterations and progressive weight loss over a period of weeks or months. consistent microscopic lesions were limited to the central nervous system and characterized by widespread spongiform transformation of the neuropil, intracytoplasmic vacuol ...19827154220
spongiform encephalopathy in free-ranging mule deer (odocoileus hemionus), white-tailed deer (odocoileus virginianus) and rocky mountain elk (cervus elaphus nelsoni) in northcentral colorado.between march 1981 and june 1995, a neurological disease characterized histologically by spongiform encephalopathy was diagnosed in 49 free-ranging cervids from northcentral colorado (usa). mule deer (odocoileus hemionus) were the primary species affected and accounted for 41 (84%) of the 49 cases, but six rocky mountain elk (cervus elaphus nelsoni) and two white-tailed deer (odocoileus virginianus) were also affected. clinical signs included emaciation, excessive salivation, behavioral changes, ...19979027685
chronic wasting disease of cervids.chronic wasting disease (cwd) has recently emerged in north america as an important prion disease of captive and free-ranging cervids (species in the deer family). cwd is the only recognized transmissible spongiform encephalopathy (tse) affecting free-ranging species. three cervid species, mule deer (odocoileus hemionus), white-tailed deer (o. virginianus), and rocky mountain elk (cervus elaphus nelsoni), are the only known natural hosts of cwd. endemic cwd is well established in southern wyomin ...200415148993
prp genotypes of free-ranging wapiti (cervus elaphus nelsoni) with chronic wasting disease.variation in prp prion gene sequence appears to modulate susceptibility to chronic wasting disease (cwd), a naturally occurring prion disease affecting four north american species of the family cervidae. wapiti (cervus elaphus nelsoni) prp is polymorphic at codon 132 [methionine (m) or leucine (l)]. we genotyped 171 samples, collected between 2002 and 2005 from cwd-infected and uninfected wapiti from three free-ranging populations in colorado, usa, to study influences of prp polymorphisms on cwd ...200818420812
gross and microscopic lesions of naturally occurring tuberculosis in a captive herd of wapiti (cervus elaphus nelsoni) in colorado.a mycobacterium bovis-infected herd of captive wapiti (cervus elaphus nelsoni) in colorado was depopulated after lesions of bovine tuberculosis were confirmed in 8 of 10 tuberculin skin test reactors. of the 43 animals > 1 year of age, 26 had gross lesions suggestive of tuberculosis, 24 had microscopic lesions of tuberculosis, and 23 had acid-fast bacilli associated with the lesions. lungs and retropharyngeal lymph nodes were the most frequently affected sites. most lesions grossly and microscop ...19921457546
a mortality event in elk ( cervus elaphus nelsoni) calves associated with malnutrition, pasteurellosis, and deer adenovirus in colorado, usa.this report describes clinical, necropsy, and ancillary diagnostic findings for a mortality event in rocky mountain elk ( cervus elaphus nelsoni) calves attributed to malnutrition, pasteurellosis, and an alimentary presentation of adenovirus hemorrhagic disease.201728328349
high elaeophorosis prevalence among harvested colorado moose.infection with elaeophora schneideri, a filarial parasite, occurs commonly in mule deer (odocoileus hemionus) and elk (cervus elaphus nelsoni), but seemingly less so in moose (alces alces). of 109 carotid artery samples from moose harvested throughout colorado, usa, in 2007, 14 (13%; 95% binomial confidence interval [bci]=7-21%) showed gross and 91 (83%; 95% bci=75-90%) showed histologic evidence of elaeophorosis. although neither blindness nor other clinical signs associated with elaeophorosis ...201323778618
efficacy of antemortem rectal biopsies to diagnose and estimate prevalence of chronic wasting disease in free-ranging cow elk (cervus elaphus nelsoni).a reliable antemortem test is needed to understand the ecology of chronic wasting disease (cwd) in elk (cervus elaphus nelsoni). we measured the ability of antemortem biopsy samples from the rectal mucosa to detect the abnormal prion protein associated with cwd (prp(cwd)), the relationship between test results from the obex and rectal biopsies at varying stages of cwd progression, and the prevalence of cwd in free-ranging elk from rocky mountain national park, colorado, usa. we sampled and place ...201323568902
epizootiology of chronic wasting disease in free-ranging cervids in colorado and wyoming.surveillance and epidemic modeling were used to study chronic wasting disease (cwd), a transmissible spongiform encephalopathy that occurs naturally among sympatric, free-ranging deer (odocoileus spp.) and rocky mountain elk (cervus elaphus nelsoni) populations in contiguous portions of northeastern colorado and southeastern wyoming (usa). we used clinical case submissions to identify endemic areas, then used immunohistochemistry to detect cwd-infected individuals among 5,513 deer and elk sample ...200011085429
surveys for disease agents in introduced elk in arkansas and kentucky.surveys for disease agents were conducted in introduced free-ranging elk (cervus elaphus nelsoni) in arkansas and kentucky. elk had been captured in colorado and nebraska and released in arkansas during 1981-1985. from 1997 through 2002 elk were captured in arizona, kansas, north dakota, new mexico, oregon, and utah and released in southeastern kentucky. specimens were collected from 170 hunter-killed elk in arkansas during 1998-2006, and 44 elk in kentucky during 2001-2004. significant findings ...201020090032
epidemiology of chronic wasting disease in captive rocky mountain elk.between june 1986 and may 1997, chronic wasting disease (cwd) was the only natural cause of adult mortality among captive rocky mountain elk (cervus elaphus nelsoni) held at a wildlife research facility near fort collins, colorado (usa). of 23 elk that remained in this herd > 15 mo, four (17%) developed cwd. all affected elk were unrelated females from the founding cohort, captured as neonates and raised in 1986. the index case was diagnosed in 1989; time intervals between subsequent cases range ...19989706562
new records of hair follicle mites (demodecidae) from north american cervidae.individuals of three species of cervids, with varying degrees of alopecia, were examined for ectoparasites: rocky mountain elk (cervus elaphus nelsoni) and mule deer (odocoileus hemionus hemionus) in colorado and white-tailed deer (odocoileus virginianus) in south dakota. hair follicle mites were recovered and identified as demodex kutzeri, a species originally described from the european red deer (cervus elaphus, from austria) and the sika deer (cervus nippon pseudaxis, captive in germany). the ...201020688655
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