| identification of shared and unique immunoglobulin e epitopes of the highly conserved tropomyosins in blomia tropicalis and dermatophagoides pteronyssinus. | tropomyosin belongs to a class of highly conserved proteins in invertebrates and vertebrates. the invertebrate tropomyosins are allergenic in man with high ige cross-reactivity and have been therefore referred to as pan-allergens. | 2002 | 12190660 |
| purification of group 2 dermatophagoides pteronyssinus allergen and prevalence of its specific ige in asthmatics. | group 2 allergens are a major cause of sensitization in patients allergic to house dust mites. this study was performed to determine the prevalence of hypersensitivity to group 2 allergens (der p 2) of dermatophagoides pteronyssinus (dp) in asthmatic patients in taiwan. to facilitate the analysis of der p 2-specific ige, we raised a panel of monoclonal antibodies (moabs) to der p 2 antigens. purified der p 2 was obtained after moab affinity column purification. there were 82 asthmatic patients ( ... | 2000 | 10729778 |
| sensitization to dust mites in children with allergic rhinitis in singapore: does it matter if you scratch while you sneeze? | previously published data established blomia tropicalis, as the major source of allergic sensitization in asthmatic children in tropical singapore. objective to define the prevalence, clinical characteristics and risk factors of species-specific mite sensitization in paediatric allergic rhinitis (ar) patients in this unique environment. | 2005 | 15836750 |
| sensitization to blomia tropicalis and dermatophagoides pteronyssinus-a comparative study between singapore and taiwan. | blomia tropicalis (bt) and dermatophagoides pteronyssinus (dp) are the predominant domestic mites species in singapore and taiwan. this study aims to characterize and compare the mite sensitization profiles in both countries. skin prick tests were performed on 203 singaporeans with dp and bt crude extracts. in vitro ige and igg4 reactivity to extracts and specific allergens (der p 1, der p 2 der p 5 and blo t 5) were determined by immunoassays. approximately 91% of the tested singaporeans were s ... | 1999 | 10697257 |
| pattern of sensitization to common environmental allergens amongst atopic singapore children in the first 3 years of life. | this study was aimed to investigate the sensitization pattern to a range of common allergens in young singaporean children. a cross-sectional study involving 75 children aged below 3 years was carried out. they presented between december 1995 and april 2000 with symptoms of asthma, rhinitis, eczema, or food allergy. their levels of allergen-specific serum ige to a panel of foods (egg white, milk, soy protein, shrimp, wheat and peanut), pet dander, dust mites and cockroaches were measured with ph ... | 2001 | 12009071 |
| mite amylase from blomia tropicalis (blo t 4): differential allergenicity linked to geographical regions. | blomia tropicalis is an important domestic dust mite in the tropics and subtropics. this study describes cdna cloning of the group 4 allergen of b. tropicalis, and the evaluation of the sensitization of this allergen in atopic populations from 2 geographic regions. | 2009 | 19033729 |
| mite component-specific ige repertoire and phenotypes of allergic disease in childhood: the tropical perspective. | sensitization to perennial aeroallergens correlates with the risk of persistent asthma (as) in children. in tropical singapore, multiple codominant species of mites abound in the indoor environment, and preferential species-specific sensitization has been associated with different phenotypes of allergic disease. we investigated the pattern of mite component-specific ige (mcsige) in children with different phenotypes of clinical allergic disease in an environment with multiple mite species exposu ... | 2011 | 21332797 |
| sensitization profiles of malaysian and singaporean subjects to allergens from dermatophagoides pteronyssinus and blomia tropicalis. | the house dust mites dermatophagoides pteronyssinus (der p) and blomia tropicalis (blo t) are the most common house dust mite species in southeast asia. to date, there have only been a few studies on the sensitization profile of the general populations in southeast asia to house dust mites. the aim of this study was to determine the profiles of der p and blo t sensitization among singaporean and malaysian subjects. | 2003 | 14646382 |