| intraerythrocytic parasites in rodent populations of connecticut: babesia and grahamella species. | a total of 612 peromyscus leucopus, 11 microtus pennsylvanicus, 21 clethrionomys gapperi, and 4 tamias striatus was collected in connecticut and examined for babesia and grahamella during 1976 and 1977. babesia antibodies were detected in sera of 9 p. leucopus collected from 4 sites. babesia parasites were not detected in the blood smears of captured rodents. subsequent splenectomy and subinoculation of blood from these rodents into susceptible animals failed to induce disease and no babesia was ... | 1979 | 512755 |
| new borrelia burgdorferi antigenic variant isolated from ixodes dammini from upstate new york. | a previously undescribed borrelia burgdorferi antigenic variant was isolated from each of four ixodes dammini larvae removed from white-footed mice, peromyscus leucopus, captured in millbrook, n.y. this site is in the northern range of the known distribution of the tick in the northeastern united states. the molecular weights of approximately 32,500 and 35,500 for outer surface a and outer surface b proteins, respectively, were distinctly higher than those for previously characterized isolates f ... | 1988 | 3183008 |
| serologic analyses of peromyscus leucopus, a rodent reservoir for borrelia burgdorferi, in northeastern united states. | an enzyme-linked immunosorbent assay (elisa) and indirect fluorescent-antibody test were used to detect antibodies to borrelia burgdorferi, the causative agent of lyme disease, in peromyscus leucopus (white-footed mouse). of the 661 mice captured in connecticut, rhode island, and new york during 1980 and 1983 to 1987, 166 (25.1%) had antibodies to b. burgdorferi by elisa. comparative analyses of 210 serum specimens, collected in areas where lyme disease is endemic, revealed a threefold differenc ... | 1988 | 3384925 |
| the prevalence and significance of borrelia burgdorferi in the urine of feral reservoir hosts. | live borrelia burgdorferi were isolated from the blood and/or urine of white-footed mice (peromyscus leucopus) collected on shelter island, new york, in 1984 and 1985. prevalence of spirochetes in urine was consistently higher than in blood or both fluids simultaneously. spirochetes remained viable for 18-24 hours in urine and were maintained in culture for one week. mice removed from the field were spirocheturic for at least 13 months. one spirocheturic mouse developed spirochetemia one month a ... | 1986 | 3577491 |
| molecular linkage of hantavirus pulmonary syndrome to the white-footed mouse, peromyscus leucopus: genetic characterization of the m genome of new york virus. | the complete m segment sequences of hantaviruses amplified from tissues of a patient with hantavirus pulmonary syndrome in the northeastern united states and from white-footed mice, peromyscus leucopus, from new york were 99% identical and differed from those of four corners virus by 23%. the serum of this patient failed to recognize a conserved, immunodominant epitope of the four corners virus g1 glycoprotein. collectively, these findings indicate that p. leucopus harbors a genetically and anti ... | 1995 | 7494337 |
| analyses of mammalian sera in enzyme-linked immunosorbent assays with different strains of borrelia burgdorferi sensu lato. | blood samples were collected from cottontail rabbits (sylvilagus floridanus), raccoons (procyon lotor), white-footed mice (peromyscus leucopus), and white-tailed deer (odocoileus virginianus) between 1977 and 1991 in southern connecticut and new york state (usa) and were tested for antibodies against eight strains of borrelia burgdorferi sensu lato in enzyme-linked immunosorbent assays. among these spirochetes were six strains of b. burgdorferi sensu stricto, one strain of b. garinii (=ip90) and ... | 1995 | 8583632 |
| histopathology of peromyscus leucopus naturally infected with pathogenic ny-1 hantaviruses: pathologic markers of hps viral infection in mice. | hantavirus research is impeded by the absence of animal models of viral pathogenesis. we have studied the histopathology of mice (p. leucopus) naturally infected with the ny-1 hantavirus on shelter island, new york. five mice were determined to be seropositive in western blotting to four corners virus nucleocapsid protein and had serum antibodies to seoul and puumala hantavirus antigens by immunofluorescence assay. hantavirus gene segments of the ny-1 hantavirus were identified in these mice and ... | 1996 | 8600313 |
| serologic evidence of infection with ehrlichia spp. in wild rodents (muridae: sigmodontinae) in the united states. | rodent (muridae: sigmodontinae) blood and sera collected from 14 states were tested for seroreactivity to a cultured isolate of the human granulocytic ehrlichiosis (hge) agent by using an indirect immunofluorescence assay. of the 1,240 samples tested, 136 (11%) were found to be reactive at titers of > or = 32. rodents with hge agent-specific antibodies were found in new york (23% of 491 samples; geometric mean endpoint titer [gmt] = 441), connecticut (11% of 100 samples; gmt = 481), california ( ... | 1998 | 9508298 |
| reservoir competence of wildlife host species for babesia microti. | human babesiosis is an increasing health concern in the northeastern united states, where the causal agent, babesia microti, is spread through the bite of infected ixodes scapularis ticks. we sampled 10 mammal and 4 bird species within a vertebrate host community in southeastern new york to quantify reservoir competence (mean percentage of ticks infected by an individual host) using real-time pcr. we found reservoir competence levels >17% in white-footed mice (peromyscus leucopus), raccoons (pro ... | 2012 | 23171673 |
| potential role of deer tick virus in powassan encephalitis cases in lyme disease-endemic areas of new york, u.s.a. | powassan virus, a member of the tick-borne encephalitis group of flaviviruses, encompasses 2 lineages with separate enzootic cycles. the prototype lineage of powassan virus (powv) is principally maintained between ixodes cookei ticks and the groundhog (marmota momax) or striped skunk (mephitis mephitis), whereas the deer tick virus (dtv) lineage is believed to be maintained between ixodes scapularis ticks and the white-footed mouse (peromyscus leucopus). we report 14 cases of powassan encephalit ... | 2013 | 24274334 |
| agents of human anaplasmosis and lyme disease at camp ripley, minnesota. | the transmission dynamics of anaplasma phagocytophilum (ap) and borrelia burgdorferi (bb) among ixodes scapularis (is) and mammalian hosts was investigated at camp ripley, an area representative of central minnesota. prevalence of white-footed mouse infection with ap and bb were 20% and 42%, respectively, with a coinfection level of 14%. peak levels of infection with both agents occurred in may. the average levels of seropositivity to ap and bb were 29.3% and 48%, respectively. of the mice infec ... | 2011 | 21867420 |
| rapid, pervasive genetic differentiation of urban white-footed mouse (peromyscus leucopus) populations in new york city. | we investigated genetic diversity and structure of urban white-footed mouse, peromyscus leucopus, populations in new york city (nyc) using variation at 18 microsatellite loci. white-footed mice are 'urban adapters' that occur at higher population densities as habitat fragments are reduced in area but have a limited ability to disperse through urbanized areas. we hypothesized that this combination of traits has produced substantial genetic structure but minimal loss of genetic variation over the ... | 2010 | 20819163 |
| factors associated with the risk of giardia species infection in two sympatric species of peromyscus mice. | an epidemiologic case-control study was conducted to identify factors that predispose peromyscus spp. to the risk of infection with giardia sp. in watersheds. a total of 200 giardia sp.-positive mice (cases) and a similar number of giardia sp.-negative mice (controls) were selected from a population 2,528 mice captured in a watershed in southeastern new york state. the giardia sp. infection status of the mice was determined by centrifugation concentration flotation and an enzyme-linked immunosor ... | 2009 | 19366280 |
| prevalence of borrelia burgdorferi in small mammals in new york state. | intensive small mammal trapping was conducted in 12 counties in new york state during 1998-2000 to investigate the prevalence and site specificity of the lyme disease spirochete, borrelia burgdorferi in, and presence of the blacklegged tick, ixodes scapularis say on, the wild mice peromyscus leucopus rafinesque and peromyscus maniculatus wagner and other small mammal species. previously captured mice (1992-1997) from throughout new york state also were recruited into the study, providing a total ... | 2006 | 17017230 |
| spatiotemporal variation in a lyme disease host and vector: black-legged ticks on white-footed mice. | we monitored population density of white-footed mice (peromyscus leucopus), burdens of immature black-legged ticks (ixodes scapularis) on mice, and infection prevalence of host-seeking ticks on six forest plots in southeastern new york state from 1995 through 1999. despite densities of mice that fluctuated two orders of magnitude, average larval and nymphal tick burdens per mouse remained remarkably constant. spatial variability in mouse density and tick burdens was modest. the total number of l ... | 2001 | 12653143 |
| cryptosporidium parvum infection involving novel genotypes in wildlife from lower new york state. | cryptosporidium, an enteric parasite of humans and a wide range of other mammals, presents numerous challenges to the supply of safe drinking water. we performed a wildlife survey, focusing on white-tailed deer and small mammals, to assess whether they may serve as environmental sources of cryptosporidium. a pcr-based approach that permitted genetic characterization via sequence analysis was applied to wildlife fecal samples (n = 111) collected from september 1996 to july 1998 from three areas i ... | 2001 | 11229905 |
| prevalence of the lyme disease spirochete in populations of white-tailed deer and white-footed mice. | the prevalence of the ixodes dammini spirochete (ids) in white-tailed deer (odocoileus virginianus) and white-footed mice (peromyscus leucopus) was studied on the eastern end of long island, new york. both species commonly occur in a variety of habitats, are preferred hosts of ixodes dammini, and can harbor the spirochetes in the blood. each animal was examined for spirochetemia, tick infestation, and ids infection rates in the ticks that were removed from it. the results obtained suggest that i ... | 1984 | 6516461 |
| habitat distribution of ixodes dammini (acari: ixodidae) an lyme disease spirochetes on fire island, new york. | the distributions of ixodes dammini spielman, clifford, piesman, and corwin and lyme disease spirochetes were studied on fire island, n.y. adult ticks were more common in high-shrub habitats (shrubby vegetation greater than or equal to 1 m high) than in grassy and lowshrub habitats (vegetation less than 1 m) in spring and fall. in the fall, adults were also common in the woods. adults were more abundant on narrow trails than in nearby vegetation. during the summer, questing nymphs and larvae wer ... | 1989 | 2724316 |
| the role of medium-sized mammals as reservoirs of borrelia burgdorferi in southern new york. | the ability of raccoons (procyon lotor), striped skunks (mephitis mephitis) and opossums (didelphis virginiana) to serve as reservoirs of borrelia burgdorferi, the spirochetal agent of lyme disease, was compared with that of white-footed mice (peromyscus leucopus). twenty-eight (28) medium-sized mammals and 34 white-footed mice were captured in westchester county, new york (usa) in summer 1986. animals were caged over pans of water for 1 to 2 days to recover engorged tick larvae (ixodes dammini) ... | 1990 | 2388356 |
| microgeographic distribution of immature ixodes dammini ticks correlated with that of deer. | in order to determine whether the small-scale distribution of immature ixodes dammini spielman et al. corresponds closely to the activity patterns of white-tailed deer, odocoileus virginianus (zimmerman), these relationships were examined in a site on long island, new york, u.s.a. we first determined the extent and temporal pattern of adult ticks feeding on deer by examining twenty-three resident deer tranquilized during september-december 1985. i. dammini adults infested deer throughout this fa ... | 1990 | 2132979 |
| evaluation of host-targeted acaricide for reducing risk of lyme disease in southern new york state. | a 2-yr evaluation of a commercial product designed to reduce the risk of lyme disease by delivering permethrin-treated cotton to white-footed mice (peromyscus leucopus) was conducted at three sites in westchester county, n.y., an area where lyme disease is endemic. we examined the numbers of host-seeking nymphal ixodes dammini spielman, clifford, piesman & corwin, the numbers of larval i. dammini infesting mice, and the proportion of nymphs infected with borrelia burgdorferi, the causative agent ... | 1991 | 1941916 |
| urban landscape genetics: canopy cover predicts gene flow between white-footed mouse (peromyscus leucopus) populations in new york city. | in this study, i examine the influence of urban canopy cover on gene flow between 15 white-footed mouse (peromyscus leucopus) populations in new york city parklands. parks in the urban core are often highly fragmented, leading to rapid genetic differentiation of relatively nonvagile species. however, a diverse array of 'green' spaces may provide dispersal corridors through 'grey' urban infrastructure. i identify urban landscape features that promote genetic connectivity in an urban environment a ... | 2012 | 22320856 |
| signatures of rapid evolution in urban and rural transcriptomes of white-footed mice (peromyscus leucopus) in the new york metropolitan area. | urbanization is a major cause of ecological degradation around the world, and human settlement in large cities is accelerating. new york city (nyc) is one of the oldest and most urbanized cities in north america, but still maintains 20% vegetation cover and substantial populations of some native wildlife. the white-footed mouse, peromyscusleucopus, is a common resident of nyc's forest fragments and an emerging model system for examining the evolutionary consequences of urbanization. in this stud ... | 2013 | 24015321 |
| urbanization shapes the demographic history of a native rodent (the white-footed mouse, peromyscus leucopus) in new york city. | how urbanization shapes population genomic diversity and evolution of urban wildlife is largely unexplored. we investigated the impact of urbanization on white-footed mice,peromyscus leucopus,in the new york city (nyc) metropolitan area using coalescent-based simulations to infer demographic history from the site-frequency spectrum. we assigned individuals to evolutionary clusters and then inferred recent divergence times, population size changes and migration using genome-wide single nucleotide ... | 2016 | 27072402 |
| signatures of positive selection and local adaptation to urbanization in white-footed mice (peromyscus leucopus). | urbanization significantly alters natural ecosystems and has accelerated globally. urban wildlife populations are often highly fragmented by human infrastructure, and isolated populations may adapt in response to local urban pressures. however, relatively few studies have identified genomic signatures of adaptation in urban animals. we used a landscape genomic approach to examine signatures of selection in urban populations of white-footed mice (peromyscus leucopus) in new york city. we analysed ... | 2017 | 28980357 |
| an experimental test of competition among mice, chipmunks, and squirrels in deciduous forest fragments. | mixed hardwood forests of the northeast united states support a guild of granivorous/omnivorous rodents including gray squirrels (sciurus carolinensis), eastern chipmunks (tamias striatus), and white-footed mice (peromyscus leucopus). these species coincide geographically, co-occur locally, and consume similar food resources. despite their idiosyncratic responses to landscape and patch variables, patch occupancy models suggest that competition may influence their respective distributions and abu ... | 2013 | 23824654 |