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white-footed mice: tick burdens and role in the epizootiology of potomac horse fever in maryland.one hundred ten white-footed mice (peromyscus leucopus) were captured on horse farms in south-central maryland, examined for ticks, and tested for specific antibodies to ehrlichia risticii, the causative agent of potomac horse fever. peromyscus leucopus were consistently infested with immature american dog ticks (dermacentor variabilis), with monthly prevalences as high as 80%. sera from all 97 p. leucopus tested for antibodies to e. risticii were negative. this indicates that p. leucopus is not ...19892668569
prospective seroepidemiology of hantaviruses and population dynamics of small mammal communities of baltimore, maryland.we used a prospective seroepidemiological study, in conjunction with a mark-release-recapture protocol, to investigate the transmission of hantaviruses in four rodent species from baltimore, maryland, from june 1984 to june 1986. a total of 1,208 captures of 762 rodents provided 984 individual blood samples. the antibody prevalence, as determined by frequency of reciprocal indirect fluorescent antibody (ifa) titers greater than or equal to 32, was 33.9% in rats (rattus norvegicus, n = 466), 28.3 ...19872891308
borrelia burgdorferi in eastern virginia: comparison between a coastal and inland locality.in virginia, borrelia burgdorferi was more prevalent in a site along the atlantic ocean, near maryland, than in an inland site near williamsburg and yorktown. at the coastal site on assateague island, b. burgdorferi was isolated from 4.2% of 475 animals sampled, including four species of small mammals. serologic tests indicated that 25-37% of the small rodents assayed had been exposed to b. burgdorferi. immunofluorescence antibody assays specific for b. burgdorferi showed spirochete infection in ...19957677212
serologic evidence of infection with ehrlichia spp. in wild rodents (muridae: sigmodontinae) in the united states.rodent (muridae: sigmodontinae) blood and sera collected from 14 states were tested for seroreactivity to a cultured isolate of the human granulocytic ehrlichiosis (hge) agent by using an indirect immunofluorescence assay. of the 1,240 samples tested, 136 (11%) were found to be reactive at titers of > or = 32. rodents with hge agent-specific antibodies were found in new york (23% of 491 samples; geometric mean endpoint titer [gmt] = 441), connecticut (11% of 100 samples; gmt = 481), california ( ...19989508298
antibodies to granulocytic ehrlichiae in white-footed and cotton mice in eastern united states.serum samples, collected from peromyscus leucopus (white-footed mouse) or peromyscus gossypinus (cotton mouse) during 1987 through 1990 in florida, georgia, maryland, mississippi, and north carolina (usa), and in 1997 in southern connecticut were analyzed by indirect fluorescent antibody (ifa) staining methods or western blot procedures for antibodies to granulocytic ehrlichiae. of the 82 sera from white-footed mice in connecticut tested by ifa methods with either the bds or nch-1 strain of the ...199910231752
mammal diversity and infection prevalence in the maintenance of enzootic borrelia burgdorferi along the western coastal plains of maryland.the primary vector of borrelia burgdorferi in north america, ixodes scapularis, feeds on various mammalian, avian, and reptilian hosts. several small mammal hosts; peromyscus leucopus, tamias striatus, microtus pennsylvanicus, and blarina spp. can serve as reservoirs in an enzootic cycle of lyme disease. the primary reservoir in the northeast united states is the white-footed mouse, p. leucopus. the infection prevalence of this reservoir as well as the roles of potential secondary reservoirs has ...200617187577
parasitic arthropods of sympatric meadow voles and white-footed mice at fort detrick, maryland.twelve species of parasitic arthropods (one sucking louse, two fleas, one tick, and eight mites) were recovered from 51 meadow voles, microtus pennsylvanicus (ord); whereas nine species (one sucking louse, one bot, three fleas, one tick, and three mites) were collected from 48 white-footed mice, peromyscus leucopus (rafinesque), live-trapped on the grounds of fort detrick, frederick county, md., during 1990 and 1991. the most commonly collected arthropods from m. pennsylvanicus were the fur mite ...19921404254
presence of multiple variants of borrelia burgdorferi in the natural reservoir peromyscus leucopus throughout a transmission season.white-footed mice (peromyscus leucopus) serve as the principal reservoir for borrelia burgdorferi and have been shown to remain infected for life. complex infections with multiple genetic variants of b. burgdorferi occur in mice through multiple exposures to infected ticks or through exposure to ticks infected with multiple variants of b. burgdorferi. using a combination of cloning and single strand conformation polymorphism (sscp), b. burgdorferi ospc variation was assessed in serial samples co ...200818399776
genetic diversity of borrelia burgdorferi sensu stricto in peromyscus leucopus, the primary reservoir of lyme disease in a region of endemicity in southern maryland.in the north central and northeastern united states, borrelia burgdorferi sensu stricto, the etiologic agent of lyme disease (ld), is maintained in an enzootic cycle between the vector, ixodes scapularis, and the primary reservoir host, peromyscus leucopus. genetic diversity of the pathogen based on sequencing of two plasmid-located genes, those for outer surface protein a (ospa) and outer surface protein c (ospc), has been examined in both tick and human specimens at local, regional, and worldw ...200616885284
longitudinal study of infection with borrelia burgdorferi in a population of peromyscus leucopus at a lyme disease-enzootic site in maryland.the maintenance of borrelia burgdorferi in a population of peromyscus leucopus was investigated from 202 mark and recapture mice and 61 mice that were removed from a site in baltimore county, maryland. borrelia burgdorferi infection was detected by culture and polymerase chain reaction (pcr) of ear tissue, and exposure to the spirochete was quantified by serology. overall prevalence of b. burgdorferi, as determined by culture and pcr of ear tissue at first capture, was 25% in the longitudinal sa ...199910348235
retrospective serosurvey for human granulocytic ehrlichiosis agent in urban white-footed mice from maryland.archived serum samples from 111 peromyscus leucopus, collected 1984-88 in baltimore city (maryland, usa), were analyzed by indirect immunofluorescence assay. sera from two (2%) individuals contained antibodies reactive to ehrlichia equi and the human granulocytic ehrlichiosis (hge) agent. this suggests that the hge agent or an antigenically related organism has been present in rodent populations in this locality for more than a decade, and was present in the region at least 12 yr before a case o ...19989476244
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