| a nucleotide substitution responsible for the tawny coat color mutation carried by the mskr inbred strain of mice. | "tawny" is an autosomal recessive coat color mutation found in a wild population of mus musculus molossinus. the inbred strain mskr carries the mutation. the causative gene mc1r(taw) of the tawny phenotype is the second recessive allele at the melanocortin 1 receptor locus and is dominant to the first recessive allele, "recessive yellow" (mc1r(e)). the mc1r(taw) gene has six nucleotide substitutions, and its forecasted transcript has three amino acid substitutions (i.e., v101a, v216a, w252c). th ... | 2005 | 15653560 |