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ecological factors rather than temporal factors dominate the evolution of vesicular stomatitis virus.vesicular stomatitis new jersey virus (vsv-nj) is a rhabdovirus that causes economically important disease in cattle and other domestic animals in endemic areas from southeastern united states to northern south america. its negatively stranded rna genome is capable of undergoing rapid evolution, which allows phylogenetic analysis and molecular epidemiology studies to be performed. previous epidemiological studies in costa rica showed the existence of at least two distinct ecological zones of hig ...19968917539
molecular epidemiology of vesicular stomatitis new jersey virus from the 2004-2005 us outbreak indicates a common origin with mexican strains.vesicular stomatitis (vs) outbreaks of unknown origin occur at 8-10-year intervals in the south-western usa with the most recent outbreak beginning in 2004. a previous study has suggested that strains causing us outbreaks are closely related to strains causing outbreaks in mexico [rodriguez (2002) virus res 85, 211-219]. this study determined the phylogenetic relationships among 116 vesicular stomatitis new jersey virus (vsnjv) strains obtained from the 2004 outbreak and from endemic areas in me ...200717554039
improvement and optimization of a multiplex real-time reverse transcription polymerase chain reaction assay for the detection and typing of vesicular stomatitis virus.an improvement to a previously reported real-time reverse transcription polymerase chain reaction (real-time rt-pcr) assay for the detection of vesicular stomatitis virus (vsv) is described. results indicate that the new assay is capable of detecting a panel of genetically representative strains of vsv present in north, central, and south america. the assay is specific for vsv and allows for simultaneous differentiation between vesicular stomatitis indiana virus and vesicular stomatitis new jers ...201020453220
apparent disappearance of vesicular stomatitis new jersey virus from ossabaw island, georgia.abstract ossabaw island, georgia, is the only reported endemic focus of vesicular stomatitis new jersey virus (vsnjv) in the united states. based on recent negative serologic results of white-tailed deer and feral swine and the failure to isolate vsnjv from lutzomyia shannoni, it appears that vsnjv is no longer present at this site. this apparent disappearance does not appear to be related to a change in l. shannoni habitat, specifically to the density of tree holes in the maritime and mixed har ...201020954866
phylogeographic characteristics of vesicular stomatitis new jersey viruses circulating in mexico from 2005 to 2011 and their relationship to epidemics in the united states.we analyzed the phylogenetic and time-space relationships (phylodynamics) of 181 isolates of vesicular stomatitis new jersey virus (vsnjv) causing disease in mexico and the united states (us) from 2005 through 2012. we detail the emergence of a genetic lineage in southern mexico causing outbreaks in central mexico spreading into northern mexico and eventually into the us. that emerging lineage showed higher nucleotide sequence identity (99.5%) than that observed for multiple lineages circulating ...201424418533
vesicular stomatitis outbreak in the southwestern united states, 2012.vesicular stomatitis is a viral disease primarily affecting horses and cattle when it occurs in the united states. outbreaks in the southwestern united states occur sporadically, with initial cases typically occurring in texas, new mexico, or arizona and subsequent cases occurring in a northward progression. the viruses causing vesicular stomatitis can be transmitted by direct contact of lesioned animals with other susceptible animals, but transmission is primarily through arthropod vectors. in ...201323883666
full-length genome analysis of vesicular stomatitis new jersey virus strains representing the phylogenetic and geographic diversity of the virus. 201222825698
domestic cattle as a non-conventional amplifying host of vesicular stomatitis new jersey virus.the role of vertebrates as amplifying and maintenance hosts for vesicular stomatitis new jersey virus (vsnjv) remains unclear. livestock have been considered dead-end hosts because detectable viraemia is absent in vsnjv-infected animals. this study demonstrated two situations in which cattle can represent a source of vsnjv to simulium vittatum zetterstedt (diptera: simuliidae) by serving: (a) as a substrate for horizontal transmission among co-feeding black flies, and (b) as a source of infectio ...201021133963
effect of mosquito salivary gland treatment on vesicular stomatitis new jersey virus replication and interferon alpha/beta expression in vitro.the sensitivity of vesicular stomatitis (vs) viruses to interferon (ifn)-mediated antiviral effects has been well documented. previous studies in our laboratory have shown the ability of mosquito saliva to enhance vesicular stomatitis new jersey (vsnj) virus infection in mice. to investigate the effect of mosquito saliva on virus replication and ifn alpha/beta expression, virus titers were analyzed at various time points after infection in cells that were treated with mosquito salivary gland hom ...200312693849
vesicular stomatitis new jersey virus glycoprotein gene sequence and neutralizing epitope stability in an enzootic focus.vesicular stomatitis new jersey (vs nj) virus is capable of undergoing rapid evolution in nature and therefore has the potential for antigenic variation. we selected an area of costa rica where vs nj virus is enzootic to study whether this virus used the mechanism of antigenic variation to persist in nature. three sentinel herds and three nonsentinel herds were observed from 1986 to 1988. eleven vs nj virus isolates were collected from naturally infected cattle. remarkably, nine animals that wer ...19901693802
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