| the rare inversion with a p element at the breakpoint maintained in a natural population of drosophila melanogaster. | we found a rare inversion which is superimposed on the in(2r) ns chromosome. it has been maintained for several years in the raleigh, n.c., usa population and possibly for more than ten years in the southern populations of the usa. both the breakpoint of the rare inversion and the corresponding site of the in(2r) ns chromosome have p elements and therefore, the rare inversion might be induced by p element activity in a natural population. | 1990 | 1963872 |
| evolutionary inferences from dna variation at the 6-phosphogluconate dehydrogenase locus in natural populations of drosophila: selection and geographic differentiation. | several allozyme-coding genes in drosophila melanogaster show patterns suggesting that polymorphisms at these loci are targets of balancing selection. an important question is whether these genes have similar distributions of underlying dna sequence variation which would indicate similar evolutionary processes occurring in this class of loci. one such locus, 6-phosphogluconate dehydrogenase (pgd), has previously been shown to exhibit clinal variation for fast/slow electromorph variation in the u ... | 1994 | 8138153 |
| nucleotide variation in the egfr locus of drosophila melanogaster. | the epidermal growth factor receptor is an essential gene with diverse pleiotropic roles in development throughout the animal kingdom. analysis of sequence diversity in 10.9 kb covering the complete coding region and 6.4 kb of potential regulatory regions in a sample of 250 alleles from three populations of drosophila melanogaster suggests that the intensity of different population genetic forces varies along the locus. a total of 238 independent common snps and 20 indel polymorphisms were detec ... | 2004 | 15280235 |
| contrasting patterns of nucleotide sequence variation at the glucose dehydrogenase (gld) locus in different populations of drosophila melanogaster. | we have analyzed nucleotide sequence variation at the glucose dehydrogenase (gld) locus from four populations of drosophila melanogaster from four continents. all four population samples show a significant reduction in silent variation compared to the neutral expectation. the levels of silent variation across all four populations are consistent with the predictions of the background selection model; however, zimbabwe has a remarkably low level of variation. in the face of dramatically reduced si ... | 1997 | 9093857 |