Publications

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malaria reemergence in the peruvian amazon region.epidemic malaria has rapidly emerged in loreto department, in the peruvian amazon region. peru reports the second highest number of malaria cases in south america (after brazil), most from loreto. from 1992 to 1997, malaria increased 50-fold in loreto but only fourfold in peru. plasmodium falciparum infection, which has increased at a faster rate than p. vivax infection in the last 3 years, became the dominant plasmodium infection in the highest transmission areas in the 1997 rainy season. the v ...199910221872
geographical distribution of anopheles darlingi in the amazon basin region of peru.malaria has reemerged as a significant public health disease threat in peru, especially within the amazon basin region. this resurgence of human cases caused by infection with plasmodium falciparum and plasmodium vivax is thought to be associated with the spread of anopheles darlingi, the principal south american malaria vector, into new areas of the amazon basin. however, comprehensive studies of the distribution for this species have not been conducted in peru for several years, nor are histor ...200314710728
limited diversity of anopheles darlingi in the peruvian amazon region of iquitos.anopheles darlingi is the most important malaria vector in the amazon basin of south america, and is capable of transmitting both plasmodium falciparum and p. vivax. to understand the genetic structure of this vector in the amazonian region of peru, a simple polymerase chain reaction (pcr)-based test to identify this species of mosquito was used. a random amplified polymorphic dna-pcr was used to study genetic variation at the micro-geographic level in nine geographically separate populations of ...200616896125
experimental infection of the neotropical malaria vector anopheles darlingi by human patient-derived plasmodium vivax in the peruvian amazon.malaria transmission from humans to mosquitoes is modulated by human host immune factors. understanding mechanisms by which the human host response may impair parasite infectivity for mosquitoes has direct implications for the development of transmission-blocking vaccines. we hypothesized that despite a low transmission intensity of malaria in the peruvian amazon region of iquitos, transmission-blocking immunity against plasmodium vivax might be common, given an unexpectedly high proportion of a ...200617038681
linking deforestation to malaria in the amazon: characterization of the breeding habitat of the principal malaria vector, anopheles darlingi.this study examined the larval breeding habitat of a major south american malaria vector, anopheles darlingi, in areas with varying degrees of ecologic alteration in the peruvian amazon. water bodies were repeatedly sampled across 112 km of transects along the iquitos-nauta road in ecologically varied areas. field data and satellite imagery were used to determine the landscape composition surrounding each site. seventeen species of anopheles larvae were collected. anopheles darlingi larvae were ...200919556558
seasonal distribution, biology, and human attraction patterns of mosquitoes (diptera: culicidae) in a rural village and adjacent forested site near iquitos, peru.this study was conducted as part of a field-ecology study of arboviral and malarial activity in the amazon basin, loreto department, peru, to determine the relative abundance, species diversity, and seasonal and vertical distributions of potential mosquito vectors. mosquitoes were captured either by volunteers using mouth aspirators while mosquitoes attempted to land on the collectors or in dry ice-baited abc light traps. anopheles darlingi, the principal malaria vector in the region, was the mo ...200819058644
the effect of deforestation on the human-biting rate of anopheles darlingi, the primary vector of falciparum malaria in the peruvian amazon.to examine the impact of tropical rain-forest destruction on malaria, we conducted a year-long study of the rates at which the primary malaria vector in the amazon, anopheles darlingi, fed on humans in areas with varying degrees of ecological alteration in the peruvian amazon. mosquitoes were collected by human biting catches along the iquitos-nauta road at sites selected for type of vegetation and controlled for human presence. deforested sites had an a. darlingi biting rate that was more than ...200616407338
risk of malaria transmission from fish ponds in the peruvian amazon.the contribution made by fish ponds (pisciculture) to malaria transmission in the peruvian amazon remains to be confirmed. recent entomological evidence indicates that anopheles darlingi, the main malaria vector in the region, is frequently found in fish ponds along the iquitos-nauta road (loreto, peru). the aim of this study was to quantify the effect of fish pond density on malaria occurrence.201020188688
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