| [polymorphisms of the pfmdr1 gene in field samples of plasmodium falciparum and their association with therapeutic response to antimalarial drugs and severe malaria in colombia]. | the pfmdr1 gene of plasmodium falciparum has been described as a gene conferring resistance to several antimalarial drugs. in particular, polymorphisms on specific codons have been associated with resistance and treatment failure with cloroquine, amodiaquine and mefloquine. however, the role of these polymorphisms in treatment response to antimalarials remains unexplored in colombia. furthermore, the relationship of these polymorphisms to severe malaria is unknown. | 2007 | 17713631 |