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development of an antigen capture immunoassay based on monoclonal antibodies specific for dengue virus serotype 2 nonstructural protein 1 for early and rapid identification of dengue virus serotype 2 infections.the dengue virus (denv) has four distinct serotypes (denv1, denv2, denv3, and denv4) that require differentiation for effective prevention of morbid diseases. the recently developed denv1-specific ns1 antigen capture enzyme-linked immunosorbent assay (elisa) based on the monoclonal antibodies (mabs) that recognize distinct epitopes on nonstructural protein 1 (ns1) of a specific denv serotype is convenient and cost-effective, but assays have not yet been developed for denv serotypes 2 to 4. this ...200919020106
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