polymorphism of intron-1 in the voltage-gated sodium channel gene of anopheles gambiae s.s. populations from cameroon with emphasis on insecticide knockdown resistance mutations. | sequence variation at the intron-1 of the voltage-gated sodium channel gene in anopheles gambiae m- and s-forms from cameroon was assessed to explore the number of mutational events originating knockdown resistance (kdr) alleles. mosquitoes were sampled between december 2005 and june 2006 from three geographical areas: (i) magba in the western region; (ii) loum, tiko, douala, kribi, and campo along the atlantic coast; and (iii) bertoua, in the eastern continental plateau. both 1014s and 1014f kd ... | 2009 | 19538340 |
spectrum of metabolic-based resistance to ddt and pyrethroids in anopheles gambiae s.l. populations from cameroon. | some populations of anopheles gambiae s.l. from cameroon were reported to develop resistance to ddt or pyrethroids but were free of the kdr mutation "leucine-phenylalanine" (leu-phe). this study reports on the metabolic activity of non-specific esterases (nses), mixed function oxidases (mfos), and glutathione s-transferases (gsts), three enzyme systems commonly involved in insecticide resistance. biochemical assays were performed in ddt or pyrethroid-resistant populations of an. gambiae s.l. fro ... | 2007 | 17633433 |