| research activities at the loma linda university and proton treatment facility--an overview. | the loma linda university (llu) radiobiology program coordinates basic research and proton beam service activities for the university and extramural communities. the current focus of the program is on the biological and physical properties of protons and the operation of radiobiology facilities for nasa-sponsored projects. the current accelerator, supporting facilities and operations are described along with a brief review of extramural research projects supported by the program. these include s ... | 2001 | 11770533 |
| molecular evolution in panagrolaimus nematodes: origins of parthenogenesis, hermaphroditism and the antarctic species p. davidi. | as exemplified by the famously successful model organism caenorhabditis elegans, nematodes offer outstanding animal systems for investigating diverse biological phenomena due to their small genome sizes, short generation times and ease of laboratory maintenance. nematodes in the genus panagrolaimus have served in comparative development and anhydrobiosis studies, and the antarctic species p. davidi offers a powerful paradigm for understanding the biological mechanisms of extreme cold tolerance. ... | 2009 | 19149894 |
| the ecology and biodemography of caenorhabditis elegans. | the nematode caenorhabditis elegans is a well-known model organism for research on aging and life span, but very little is known about its ecology and natural history. the strain n2 is the standard wild-type c. elegans and arose from the progeny of a single hermaphrodite. since n2 has passed through laboratory culture, the influence of inadvertent selection and genetic drift on c. elegans strains kept in culture is unclear. because it seems that other wild-type strains have also been subject to ... | 2006 | 16963216 |
| caenorhabditis elegans and friends in los angeles. | | 2005 | 16277759 |
| foxo3 and related transcription factors in development, aging, and exceptional longevity. | in june 2013, a workshop was convened in san francisco to explore, in depth, the role of the forkhead transcription factor foxo3 (and related foxos) in development, aging, and, in particular, exceptional longevity. the presentations covered results derived from model systems, computational analysis and bioinformatics, and genomics and genome-wide association studies of a number of cohorts. although the data collectively strongly reinforce foxo3 and the foxo/foxo3 pathway as very important determ ... | 2015 | 24747665 |