| haplotype analysis of the delta 2642 and (cag)n polymorphisms in the huntington's disease (hd) gene provides an explanation for an apparent 'founder' hd haplotype. | the discovery of the intragenic delta 2642 deletion/insertion polymorphism in the huntington's disease (hd) gene provides a tool to explore hd evolution, as the deletion is rare in normal chromosomes but overrepresented in hd chromosomes. thus, delta 2642 deletion alleles were thought to mark normal chromosomes that are particularly prone to becoming hd chromosomes. we have examined this polymorphism in a range of human and non-human primate populations. our results suggest that the deletion eve ... | 1995 | 7757068 |