| ebola virus infection in imported primates--united states. | in late november 1989, ebola virus was isolated from cynomolgus monkeys (macaca fascicularis) imported into the united states from the philippines via amsterdam and new york. during quarantine in a primate facility in virginia, numerous macaques died, some with findings consistent with simian hemorrhagic fever (shf). the us army medical research institute of infectious diseases tested 10 animals and, from 3, isolated shf from tissues and serum; however, 5 other animals of the 10 tested were posi ... | 1990 | 2302743 |
| attenuated nycbh vaccinia virus deleted for the e3l gene confers partial protection against lethal monkeypox virus disease in cynomolgus macaques. | the new york city board of health (nycbh) vaccinia virus is the currently licensed vaccine for use in the us against smallpox. the vaccine under investigation in this study has been attenuated by deletion of the innate immune evasion gene, e3l, and shown to be protective in homologous virus mouse challenge and heterologous virus mouse and rabbit challenge models. in this study we compared nycbh deleted for the e3l gene (nycbhδe3l) to nycbh for the ability to induce phosphorylation of proinflamma ... | 2011 | 22001879 |