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molecular cloning and in vitro evaluation of an infectious simian-human immunodeficiency virus containing env of a primary chinese hiv-1 subtype c isolate.human immunodeficiency virus (hiv) clade c is the most prevalent subtype and accounts for approximately 50% of all hiv infections worldwide. in china, the prevalent hiv strains are b'/c subtypes, in which the envelope belongs to subtype c. to evaluate potential aids vaccines targeting chinese viral strains in non-human primate models, we constructed an infectious simian-human immunodeficiency virus (shiv) that expresses most of the envelope of a primary hiv strain, which was isolated from a hiv- ...200515860117
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